64排螺旋CT检测冠状动脉粥样硬化斑块与血管重构及ACS的相关性研究  

Rsearch on the Relationship Between Coronary Atherosclerotic Plaque and Vascular Remodeling,Acute Coronary Syndrome by 64-slice Spiral CT

作　　者：齐晨晖[1] 孙志国[1] 赵庆[1] 侯艳军[1] QI Chen-hui,SUN Zhi-guo,ZHAO Qing,HOU Yan-jun（The No.2People＇s hospital in Jiaozuo,Jiaozuo 454000,China）

机构地区：[1]焦作市第二人民医院,河南焦作454000

出　　处：《医学信息》2010年第16期2565-2567,共3页Journal of Medical Information

摘　　要：目的探讨64排螺旋CT检测冠状动脉粥样硬化斑块的临床应用价值。方法收集在本院行64排SCT冠状动脉成像,临床确诊为冠心病患者78例,分为急性冠脉综合征（acute coronary syndrome,ACS）和稳定性心绞痛（stable angina pectoris,SAP）两组,对检出的动脉粥样硬化斑块影像学特征进行分析,分析动脉粥样硬化斑块与血管重构及ACS之间的相关性。结果 78例患者共检测到斑块256个,其中软斑块65个,中间斑块81个,钙化斑块110个;有软斑的冠状动脉正向重构率明显高于钙化斑块的冠状动脉正向重构率,有显著统计学差异（P〈0.01）。ACS以软斑和中间斑块为主,SAP组以钙化为主,ACS组冠状动脉正向重构率明显高于SAP组,且均有显著统计学差异（P〈0.01）。结论冠状动脉粥样硬化斑块性质与血管重构及ACS有明显相关性,64排螺旋CT检测冠状动脉粥样硬化斑块具有较高的临床价值,可作为评价冠心病危险度的一种无创检查技术。Objective To explore the clinical application value of 64-slice spiral CT detected coronary atherosclerotic plaques.Methods 78 patients confirmed clinically to be coronary heart disease and all underwent 64-slice spiral computed tomography coronary angiography were divided into acute coronary syndrome and stable angina pectoris two groups,the correlation between atherosclerotic plaque imaging features and vascular remodeling and the correlation ACS were analyzed.Results Of the 78 patients,256 plaques were detected,including soft plaque 65,moderately attenuated 81,calcified plaque 110;The positive reconstruction rate of the coronary artery with soft plaque was significantly higher than that of coronary artery calcification,and there was significant statistical difference（P 0.01）.Culprit lesions of ACS were predominantly soft and intermediate density plaque,but Culprit lesions of SAP were predominantly calcified plaque,The positive rate of vascular remodeling of ACS group was significantly higher than that of SA group and all were statistically significant（P 0.01）.Conclusion There is significant correlation between the nature of coronary atherosclerotic plaque and vascular remodeling and ACS,64-slice spiral CT detect coronary atherosclerotic plaque with a high clinical value,and can be used as a non-invasive screening techniques to predict the risk of coronary heart disease.

关 键 词：64排螺旋CT 冠状动脉硬化 斑块 急性冠脉综合征 

分 类 号：R543.3[医药卫生—心血管疾病;医药卫生—临床医学;医药卫生—内科学]