医院感染病原菌的分布及耐药性分析  

Analysis of distribution and antibacterial resistance of nosocomial infection pathogens in Hospital

作　　者：郝继晖[1] 申亚丽[1] 

机构地区：[1]北京市第六医院,北京100007

出　　处：《中国临床药理学杂志》2010年第7期506-509,共4页The Chinese Journal of Clinical Pharmacology

摘　　要：目的调查及分析医院感染病原菌的分布及耐药趋势。方法对住院患者各类标本中分离出的病原菌,进行细菌鉴定和药敏实验,并进行归纳与分析。结果共分离病原菌1521株(真菌除外);革兰阳性球菌255株(16.77%),以葡萄球菌属为主,未发现耐万古霉素菌株。革兰阴性杆菌1266株(83.23%),以铜绿假单胞菌、大肠埃希菌多见;革兰阴性杆菌对碳青酶烯类耐药率最低。结论医院感染的耐药问题日趋严重,定期进行细菌耐药性监测,对指导临床合理应用抗菌药物,控制医院感染具有重要意义。Objective To investigate the tendency of bacterial distribution and resistance of hospital infections. Methods Bacteria isolated from patients in our hospital were identified and bacterial susceptibility tests were performed. Results A total of 1521 pathogens strains were isolated,among them 255 strains were （16. 77% ）. The most common pathogens of them were Staphylococcus. In our data , no vancomycin resistant S. aureus were isolated. There were 1266 strains of Gram - negative bacilli （ 83.23 % ）, the most common pathogens of them were Pseudomonas aeruginosa and Escherichia coli. The highest susceptible to Gram -negative bacilli was carbapenem. Conclusion Drug resistance of the nosocomial infection bacteria is a serious problem. It is important and urgent to carry out surveillance of bacterial resistance for appropriate using of antibiotics and effective controlling nosocomial infections.

关 键 词：医院感染 病原菌分布 耐药性监测 

分 类 号：R978.1[医药卫生—药品] R969.3[医药卫生—药学]