单肺麻醉期间非通气侧肺吹入氧化亚氮对肺内分流的影响  

Effects of non-ventilated lung insufflated with nitrous oxide on intrapulmonary shunt during one lung anesthesia

作　　者：邵贵骞[1] 李志学[1] 李继学[1] 张云安[1] 曲仁海[1] 

机构地区：[1]哈尔滨医科大学附属第一医院,150001

出　　处：《中华麻醉学杂志》1999年第1期36-38,共3页Chinese Journal of Anesthesiology

摘　　要：目的　探讨单肺麻醉期间对非通气侧肺吹入氧化亚氮 ( N2 O)对减少肺内分流、预防低氧血症的作用。方法　择期开胸手术病人 2 2例 ,随机分两组 :观察组、对照组各 11例。在单肺麻醉期间非通气侧肺吹入 N2 O,并在单肺通气后 3 0及 60分 ,分别采动脉血作血气分析 ,计算分流率 ( Qs/Qt)。在单肺麻醉期间非通气侧肺的支气管导管开口于大气中 ,并在单肺通气 3 0及 60分分别采动脉血作血气分析并计算 Qs/ Qt。结果　在单肺麻醉 3 0、60分时 ,A组 Qs/ Qt显著低于 B组 ( P<0 .0 5 )。结论　单肺麻醉期间 ,对非通气侧肺吹入 N2 O可以明显减少肺内分流 。Objective To investigate the effects on intrapulmonary shunt when non ventilated lung was insufflated with nitrous oxide (N 2O) during one lung ventilation (OLV) Methods Twenty two ASA grade Ⅰ Ⅱ patients undergoing thoracic surgery were randomly divided into two groups:observation group (group A,n=11) and controlled group (group B,n=11) Group A:N 2O was insufflated into the non ventilated lung during OLV;Group B:the non ventilated lung was kept open to the air,and the blood gases of all patients were analysed seperately before anesthesia,30min and 60min following OLV to calculate the shunt ratio (s/t) Results s/t in group A was decreased significantly more than in group B during OLV (P<0 05) Conclusion Non ventilated lung was insufflated with N 2O during OLV can reduce intrapulmonary shunt and prevent hypoxemia

关 键 词：氧化亚氮吸入 肺内分流 麻醉 单肺麻醉 

分 类 号：R614.2[医药卫生—麻醉学]