兰盆花黄酮类抗氧化作用  

Antioxidation of Flavonoids of Scabiosa Comosa Fisch

作　　者：乌日娜[1] 张维兰[1] 孙福祥[1] 张昕原[1] 巴根那[1] 王志民[1] 李宝山[1] 

机构地区：[1]内蒙古蒙医学院中心实验室

出　　处：《时珍国医国药》1999年第1期23-24,共2页Lishizhen Medicine and Materia Medica Research

摘　　要：兰盆花黄酮类化合物在ＶＢ２－Ｍｅｔ－ＮＢＴ体系中对Ｏ－·２的ＩＣ５０为２．７μｇ／ｍｌ，ＳＣ５０２．５μｇ／ｍｌ，在Ｖｉｔ．Ｃ－ｃｏｐｐｅｒ－ｃｙｔ．ｃ体系中．ＯＨＲ５０为１４．６μｇ／ｍｌ在Ｆｅ２＋／Ｈ２Ｏ２体系中能抑制ＭＤＡ生成。其清热的功效很可能与其清除Ｏ－·２、．ＯＨ、ＭＤＡ的抗氧化作用有关。Flavonoids compounds of Scabiosa comosa Fisch had antioxidation to O -· 2 (IC 50 =2.7μg/ml,SC 50 =2.5μg/ml) in the system of VB 2-Met-NBT, to·OH (SC 50 =14.6 μg/ml)in the system of Vit.C-copper-cyt.c,could inhibited the produce of MDA in the system of Fe 2+ /H 2O 2.Their antipyretic effect would have relation to the effect of scavenging O -· 2、·OH、MDA.

关 键 词：兰盆花黄酮 阴离子氧自由基 羟自由基 丙二醛 

分 类 号：R291.2[医药卫生—民族医学] R285[医药卫生—中医学]