海南青牛胆化学成分与药理作用研究进展  

Research progress on chemical constituents and pharmacological activities of Tinospora hainanensis

作　　者：吴丽媛[1] 关世侠[1] 姜月霞[2,3] 刘明生[2,3] 

机构地区：[1]广州中医药大学,广东广州510006 [2]海南医学院热带药用植物研究开发省重点实验室,海南海口571101 [3]海口市黎族医药重点实验室,海南海口571101

出　　处：《现代药物与临床》2010年第3期177-180,共4页Drugs & Clinic

基　　金：国家科技支撑计划(2007BAI27B05)

摘　　要：海南青牛胆中结构明确的化学成分主要包括甾酮类化合物、季铵类生物碱、挥发油、游离氨基酸、无机元素及其他类化合物。药理实验证明其安全,无毒副作用,并有抗骨质疏松及消除关节炎产生的关节肿胀,缓解疼痛,抑制炎症的作用。就海南青牛胆的国内外研究进展进行了综述,为今后研究与应用该植物提供参考。This paper summarizes the researches on Tinospora hainanensis H. S. Lo et Z. X. L. conducted in China and foreign countries, so as to provide certain scientific basis for further research and development of T. hainanensis. The chemical constituents with clear structures are mainly divided into the following types, sterone compounds, quaternary ammonium alkaloid, volatile oils, free amino acids, inorganic elements and others. Pharmacological experiments show that T. hainanensis is safe in use and do not have toxic or side effects. T. hainanensis has certain positive effects on osteoporosis, and can also eliminate joint swelling, relieve pains and inhibit inflammation induced by arthritis.

关 键 词：海南青牛胆 甾酮类化合物 季铵类生物碱 抗骨质疏松 

分 类 号：R282.71[医药卫生—中药学]