腰椎间盘突出症术后血流变学变化及临床意义  

Postoperative Change of Hemorheology in Patients with Lumbar Disc Herniation and Its Clinical Significance

作　　者：赵长庚[1,2] 曲春杰 范家骏[1,2] 雷泽著[1,2] 周勇刚 张永刚[1,2] 

机构地区：[1]解放军202医院 [2]西安第四军医大学

出　　处：《中国骨伤》1999年第1期14-16,共3页China Journal of Orthopaedics and Traumatology

摘　　要：目的研究腰椎间盘突出症术后血流变学的变化及其临床意义。方法对５２例腰椎间盘突出症手术前后检测１０项血流变学指标，配对比较８项指标（Ｐ＜０．００１）。血流变指标与影响因素作多元回归分析。结果手术时间长、损伤重对红细胞比积降低影响大（Ｐ＜０．０５），血沉及血沉方程Ｋ值升高与输液量有关（Ｐ＜０．０５）。结论术后不同时间血流变学变化存在着创伤应激反应使血粘度等指标升高和血液稀释使其降低两方面因素的影响。提示外科失血不宜等量输血，应“欠量”输血，适当补液维持低红细胞比积状态。Objective To study the postoperative changes of hemorheology in patients with lumbar disc herniation and its clinical significance.Methods Ten hemorheological parameters were measured in 52 patients with lumbar disc herniation prior to and after discectomy.The data were treated statistically with paired t test and multiple regression analysis.Results The long period of operation and the major trauma of surgery made evident influence on the decrease of hematocrit (P<0 05).The increase of ESR and ESR K value was related to the volume of fluid infusion(P<0 05).Conclusion The changes of hemorrheology at different postoperative time points were affected by two factors,i.e. traumatic stress leads to the increase of the blood viscosity and other parameters,while the dilution of the blood leads to the decrease of the blood viscosity and other parameters.It was suggested for treating surgical bleeding that the volume of blood transfusion would be rather less than that of blood loss,and the supplement with the right amount of fluid infusion to keep a low hematocrit is benificial to prevent some complications.

关 键 词：血液流变学 腰椎间盘突出症 治疗 外科手术 

分 类 号：R681.530.2[医药卫生—骨科学]