HPLC法测定6厂家血脂平胶囊中的丹皮酚含量  

To Determine Danpifen Content in Xiezhiping Jiao Nang from6 Different Manufacturers by HPLC

作　　者：高厚明[1] 刘纪清[1] 熊明玲[1] 

机构地区：[1]深圳市中医院药学部,深圳518033

出　　处：《中国医药导刊》2010年第7期1268-1270,共3页Chinese Journal of Medicinal Guide

摘　　要：耳的：实验研究不同厂家生产的血脂平胶囊的产品质量和临床疗效差异的原因。方法：采用HPLC法测定6个厂家的斑脂平胶囊中丹皮酚含量，丹皮酚对照品检测浓度在0．1332～2：664μg／ml范围内，线性关系良好（r=29998），平均回收率99．38％,RSD≤1.08％。结果：6个厂家血脂平胶囊每粒丹皮酚含量在1．089～1．794mg之间，质量尚可。结论：6个厂家血脂平胶囊丹皮酚含量每粒在1．0mg以上，但高低相差64．7％，P〈0．01。产品质量有极明显差异。Objective：The experiment was performed to study the quality of Xiezhiping Jiao Nang from different manufacturers,and causes of different for clinical efficacy.Methods：Danpifen content of Xiezhiping Jiao Nang from 6 different manufacturers was determined by HPLC.The linear range of Danpifen control was 0.1332～2.664μg/ml（r=0.9998）,avemge recovery was 99.38% （RSD〈1.08%）.Results：Danpifen content of each Xiezhiping Jiao Nang from 6 different manufacturers was 1.089～1.794mg,with fine quality.Conelusion：Danpifen content of each Xiezhiping Jiao Nang from 6 different manufacturers was above 1.0mg, but difference between the maximum and mimmum was observed to be 64.7% （P〈0.01）,the quality of each product is quite different from one another.

关 键 词：HPLC法 不同厂家 血脂平胶囊 丹皮酚含量 

分 类 号：R286.0[医药卫生—中药学]