大气飘尘中不同有机组分致突变性  

MUTAGENIC STUDY ON DIFFERENT ORGANIC FRACTIONS OF AIR PARTICULATE EXTRACT

作　　者：朱惠刚[1] 赵启宇[1] 蒋颂辉[1] 

机构地区：[1]上海医科大学

出　　处：《上海环境科学》1990年第12期18-22,共5页Shanghai Environmental Sciences

摘　　要：采用化学分离与Ames试验相结合的方法,研究了上海市飘尘中粗提物5个有机组分的致突变性。结果表明,其中以极性化合物(F_3)组分致突变性最强,约占76％～86％;其次为有机碱(F_2)化合物组分,占10％～19.6％;多环芳烃化合物(包括Bap)组分致突变性最小,仅占2.6％～11％;脂肪烃(F_4)没有致突变性;F_1主要组分有机酸,在25μg/皿低剂量时,仍出现抑菌现象,其致突变性尚准确定。研究结果提示了环境致癌因子的来源。In this paper, a result of mutagenic effect of different fractions isolated from air particulates in Shanghai was reported. It was demonstrated that the polar compounds had a strongest mutagenicity than all other components, and accounted for 76～86% of mutagenic intensity, the alkali part mainly composed of organic alkaloids showed a second order of mutagenic intensity equivalent to a ratio of 10～19.6%, while the aromatic hydrocarbons.included PAH as well as benzopyrene only showed a weak portion equivalent to 2.6～11% of mutagenic intensity in whole mutagenic constituents. Whether the acidic part separated from air particulates had a mutagenic effect was not demonstrated, because this part showc~ an inhibitory action to Salmonella strains even the dose was lowered to the amount of 2o μg,disc. As to aliphatic components, no mutagenic effect was observed in Ames assay.

关 键 词：大气 飘尘 致突变性 

分 类 号：X513.02[环境科学与工程—环境工程]