不同屈曲角度下膝关节主要韧带有限元模型的建立和验证  

Construction and validation of a finite element knee joint model of major ligaments at different flexion angles

作　　者：钟砚琳[1] 王海鹏[1] 容可[1] 王友[1] 谢叻[2] 

机构地区：[1]上海交通大学医学院附属第九人民医院骨科,上海市骨科内植物重点实验室,上海市200011 [2]模具CAD国家工程研究中心,上海市200240

出　　处：《中国组织工程研究与临床康复》2010年第30期5515-5518,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：国家"863"计划资助项目(2006AA01Z310);上海市骨科内植物重点实验室建设基金资助项目(08DZ2230330)~~

摘　　要：背景:随着计算机技术和有限元理论的发展,通过建立膝关节主要韧带的有限元模型进行生物力学研究开始成为最重要的研究方法之一,而如何建立不同屈曲角度下的精确而有效的膝关节模型也成为了研究者们关注的焦点。目的:探索建立不同屈曲角度下膝关节主要韧带有限元模型的方法并进行验证。方法:解剖膝关节标本,去除周围软组织并暴露主要韧带。将韧带用钢丝环绕标记后用CT机在不同屈曲角度下扫描,去除韧带组织后再将韧带止点打孔标记并用CT机扫描。将得到的图像数据导入到仿真软件MIMICS中进行三维重建。将三维模型进行必要的修饰和调整后导入有限元软件ANSYS中,在设置材料属性和划分网格后生成三维有限元模型。在有限元软件中对完全伸直角度下的有限元模型采用134N前向力作用于胫骨,采集胫骨前移的数据并观察韧带受力情况以验证模型的有效性。结果与结论:得到的模型外形精确逼真,包括股骨、胫骨、前后交叉韧带和内外侧副韧带,并且通过与其他学者的类似数据以及临床经验的比较验证了模型的有效性。实验所得到的模型具有较好的形态仿真和功能仿真,能够在不同屈曲角度下有效的模仿膝关节活动,可以用于开展进一步的生物力学研究。BACKGROUND：With development of computer technique and finite element theory,finite element model of main knee joint ligament has been used for biomechanical studies.The establishment of accurate and effective models of knee joint under different flexion degrees has become a focus.OBJECTIVE：To explore the way to construct and validate the finite element model of the major ligaments around knee at different flexion angles.METHODS：The knee joint specimen was dissected,and the peripheral soft tissues were removed to expose the major ligaments.The ligaments were wrapped with steel wire and scanned with CT scanner at different flexion angles.The insertion site was marked after removing all the ligaments by punching holes in the bones and scan again.The image data were input into the software MIMICS for three-dimensional reconstruction.The model was input into finite element software ANSYS after modification and adjustment,and the three-dimension finite element model was generated by setting the material property and dividing the body grid.134 N anterior load was applied on the tibia to the model at full flexion angles in the software.The data of tibial anterior movement were collected,and the stress distribution was observed to validate the model.RESULTS AND CONCLUSION：The established model contained the elements of femur,tibia,anterior-posterior cruciate ligament and medial-lateral collateral ligament,and the model was validated by comparing with those of the other scientists and clinical experience.The model has good figure and function simulation,which can simulate knee movements at different flexion angles and can be used in further biomechanical study.

关 键 词：膝关节 韧带 有限元模型 验证 屈曲角度 

分 类 号：R318[医药卫生—生物医学工程]