生物组织传热红外热成像的三维温度场重建  

Infrared thermography based 3D temperature field reconstruction of biological tissue heat transfer

作　　者：马国军[1,2] 江国泰[1] 孙兵[1] 

机构地区：[1]同济大学生命科学与技术学院,上海市200092 [2]江苏科技大学电子信息学院,江苏省镇江市212003

出　　处：《中国组织工程研究与临床康复》2010年第30期5614-5617,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：国家自然科学基金项目(50977064);课题名称:脉冲变频电磁场的生物热效应及其对乳腺癌细胞杀伤作用~~

摘　　要：背景:红外热成像技术作为新型的非接触测温方法,具有无损、快捷、方便的特点,并且可以利用计算机技术对生物组织内部温度场进行三维重构。目的:针对肿瘤热疗过程中温度场测量与重构,提出生物组织温度场三维重建新方法。方法:首先根据生物传热和红外热辐射信息,采用红外热成像技术非接触测量分层体模的二维温度分布信息;然后,将此温度信息转换为人眼可视的灰度图,并进行伪彩色处理,同时,利用传输函数为热像图序列的每一个像素重新分配颜色和不透明度,从而对分层体模的温度场利用体绘制光线投射算法进行三维重建。结果与结论:实验结果表明,依据红外热辐射的原理,采用红外热像仪接受红外信息并将其转换为温度值,然后采用伪彩色显示方法,对分层体模的三维温度场进行光线投射重建,为热疗过程中生物组织内部三维温度场的测量、观测提供了新的技术手段与方法。BACKGROUND：Infrared thermography as a new technology for non-contact temperature measurement has the advantage of non-invasive,fast and convenient.And computer can be used to reconstruct 3D inner temperature field of biological tissue.OBJECTIVE：For measurement and reconstruction of temperature field in tumor hyperthermia,to propose new methods of 3D temperature field reconstruction for biological tissue.METHODS：Infrared thermography technology was applied to measure 2D temperature distribution non-contactly of sliced-biomaterial,which based on bi-heat transfer and information of infrared thermal emitter.Temperature information was converted to gray images to be visualized,and pseudo-colorly processed.In addition,every pixel in infrared thermograph was allocated color and opacity by transfer function,so as to reconstruct temperature field of sliced-biomaterial by volume rendering ray casting algorithm.RESULTS AND CONCLUSION：Experiment results showed that,based on algorithm of infrared thermal emitter and information obtained from thermal infrared imager was converted to temperature and displayed as pseudo-color.And 3D temperature field obtained from sliced-biomaterial was reconstructed with ray casting.It provides new technology and method for measurement and observation of temperature field in hyperthermia.

关 键 词：生物传热 Pennes方程 温度场 三维重建 数字化医学 

分 类 号：R318[医药卫生—生物医学工程]