人工膝关节置换后的假体周围感染  

Periprosthetic infection following artificial knee replacement

作　　者：方恺[1] 

机构地区：[1]上海市第九人民医院骨科,上海市200011

出　　处：《中国组织工程研究与临床康复》2010年第30期5650-5653,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：目的:总结近年有关人工膝关节置换后出现假体周围感染的现状。方法:由作者应用计算机检索维普数据库中与人工膝关节置换后出现假体周围感染有关的文献,检索时限1998-01/2009-10。检索词:膝关节;全膝置换;感染。对资料进行初审,并查看每篇文献后的引文。共入选18篇文献进一步分析。结果:膝关节置换后持续性疼痛和进行性关节僵直应高度怀疑深部感染。血沉、C-反应蛋白及关节穿刺物的培养是诊断感染的重要指标。单纯使用抗生素治疗不能去除深部感染,并且预后较差。使用抗生素骨水泥进行Ⅱ期翻修是去除感染的最有效治疗方案。结论:全膝关节置换后感染是十分严重的并发症,一旦发生感染应及早进行诊断,同时根据病情选择合适的治疗方案。OBJECTIVE：To summarize current state of periprosthetic infection following artificial knee replacement.METHODS：A computer-based online search of VIP was performed for articles related to periprosthetic infection following artificial knee replacement published between January 1998 and October 2009,with the key words ＂knee joint,total hip replacement,infection＂.The data were collected,and references of each article were reviewed.A total of 18 articles were included.RESULTS：Continuous pain and progressive joint stiffness following knee replacement may be a result of infection.Blood sedimentation,C-reactive protein and culture of joint drainage are main indexes of infection.Antibiotics alone cannot treat deep infection,and the prognosis is not favorable.Antibiotic-loaded articulating cement is an effective therapy for injection in revision at stagy II.CONCLUSION：Infection following total knee replacement is very severe complication.It is necessary to diagnose infection early and treat using appropriate methods based on condition of disease.

关 键 词：膝关节 假体置换 感染 并发症 医学植入体 

分 类 号：R318[医药卫生—生物医学工程]