宫颈糜烂脱落细胞IL-8表达的半定量研究  

Semiquanitatilly study of IL 8 gene expression in exfoliative cells of cervical erosion

作　　者：张仙鹤[1] 王晶[1] 牛战琴[1] 张开明[2] 

机构地区：[1]山西医科大学第一医院妇产科 [2]太原市中心医院免疫室

出　　处：《中国免疫学杂志》1999年第2期92-93,95,共3页Chinese Journal of Immunology

摘　　要：目的：探讨ＩＬ８与宫颈炎症的关系。方法：采用ＲＴＰＣＲ法对糜烂及正常宫颈的脱落细胞和血清ＩＬ８进行测定。结果：发现患者与正常人的宫颈脱落细胞ＩＬ８扩增后均为阳性，经模板稀释后患者阳性率为７３％，正常为２１％，差别显著，但血清ＩＬ８测定无明显差异。结论：认为ＩＬ８在宫颈炎症中起重要作用。Objective:To investigate the relationships between IL 8 level and cervical erosion.Methods:RT PCR was used to study the difference of IL 8 gene expression in cervical exfoliative cells and in sera from patients with cervical erosion and normals.Results:After template dilution,positive IL 8 gene expression in exfoliative cells of patients with cervical erosion was 73% and normal controls 21%,the difference is significant.But there is no difference of IL 8 levels in sera from both groups.Conclusion:IL 8 is significant in the cervical erosion.

关 键 词：宫颈糜烂 IL-8 基因扩增术 基因表达 

分 类 号：R711.320.2[医药卫生—妇产科学]