睫状神经营养因子对视神经损伤的修复作用  

The repair effect of ciliary neurotrophic factor on the injury of optic nerve

作　　者：黄靓[1] 马海英[2] 孔力[2] 

机构地区：[1]大连医科大学 [2]大连医科大学组织学与胚胎学教研室,辽宁大连116044

出　　处：《解剖科学进展》2010年第4期360-363,共4页Progress of Anatomical Sciences

基　　金：国家自然科学基金资助项目(No30850001);辽宁省自然科学基金资助项目(No20072167)

摘　　要：视神经损伤后,视网膜神经节细胞进行性损害,轴突变性坏死,再生困难。睫状神经营养因子是一种非靶源性神经营养因子,在视网膜神经节细胞的生长发育中起重要调控作用,主要表现在对损伤的视网膜神经节细胞有促进存活及轴突再生的作用。Retina1 ganglion cells will be damaged constantly with axon degeneration and even necrosis and difficult regeneration of axons after the optic nerve is injuried. Ciliary neurotrophic factor is a non-target-derived neurotrophic factor, plays an important role in regulating the growth and development of retinal ganglion cells, mostly and in promoting the repair of the injured retinal ganglion cells and axonal regeneration.

关 键 词：睫状神经营养因子 视神经损伤 修复作用 视网膜神经节细胞 靶源性神经营养因子 轴突再生 进行性损害 变性坏死 

分 类 号：R339.146[医药卫生—人体生理学]