多普勒组织成像对老年扩张型心肌病患者左室功能的评价  

The assessment of left ventricular function by use of doppler tissue imaging in elderly patients with dilated eardiomyopathy

作　　者：吴静[1] 方祖伦[1] 朱昱思 张巳声[1] 龚念梅[1] 

机构地区：[1]南通大学附属南通第三医院超声科,226006 [2]武警上海总队医院特检科

出　　处：《中华老年医学杂志》2010年第7期551-554,共4页Chinese Journal of Geriatrics

摘　　要：目的 应用多普勒组织成像（doppler tissue imaging,DTI）技术评价老年扩张型心肌病（dilated cardiomyopathy,DCM）患者左室舒缩功能,并探讨其临床应用价值.方法 采集健康老年人20例（对照组）和老年DCM患者22例（DCM组）.用常规超声心动图分别测量左审舒张末期内径（LVEDd）、左房内径（LAD）和左室射血分数（LVEF）;在DTI模式下,用定量组织速度图（QTVI）分别测量二尖瓣环水平6个位点的收缩期峰值速度（Vs）和舒张早期峰值速度（Ve）,并计算其平均值;用组织追踪图（TTI）显示二尖瓣环水平6个位点收缩期位移（mvd）,并计算其平均值.结果 DCM患者LVEDd（67.56±10.27）mm、LAD（49.91±6.27）mm,较对照组[43.36±4.20）mm、（32.00±4.53）mm]明显增大（t值分别为10.229、10.359,均P〈0.01）;LVEF（26.50±8.25）%、Vs（5.14±1.30）cm/s、mvd（4.82 4±1.85）mm.均较对照组[64.00±4.72）%、（8.89±1.87）cm/s、（10.23±1.95）mm]减低（t值分别为18.502、7.716,8.143.均P〈0.01）;Vs、mvd与LVEF呈显著正相关（r值分别为0.78、0.89.均P〈0.01）.结论 DTI可以直观、准确评价老年DCM患者左室整体和局祁的舒缩功能,为判断病情提供可靠的信息依据.Objective To quantitatively assess the left ventricular systolic and diastolic function in the elderly patients with dilated cardiomyopathy （DCM） by using Doppler tissue imaging （DTI） and to explore its clinical value. Methods A total of 20 normal controls and 22 old patients with DCM were enrolled in the study. The left ventricular end-diastolic diameter （LVEDd）, left atrial diameter （LAD） and left ventricle ejection fraction（LVEF） were obtained by routine echocardiogram. And the systolic and early diastolic peak velocity （Vs and Ve） were detected by quantitative tissue velocity imaging （QTVI） and the mean value was accounted. The systolic mitral valve displacements （MVD） in 6 sites were determined by tissue tracking technique and the mean value was calculated. Results The LVEDd and LAD were significantly higher in DCM group than in normal group [LVEDd： （67.56±10.27） mm vs. （43.36±4.20） mm; LAD： （49.91± 6.27） mm vs. （32.00±4.53） mm, t=10.229 and 10.359, both P〈0.01]. And the LVEF, Vs and MVD were lower in DCM group than in normal group [LVEF： （26.50 ± 8.25）% vs. （64.00 ± 4.72）%; Vs：（5.14±1.30） cm/s vs. （8.89±1.87） cm/s; MVD：4.82±1.85 vs. 10.23± 1.95, t=18.502, 7.716 and 8.143, all P〈 0.01].The Vs and MVD were significantly positively correlated with LVEF （r=0.78 and 0.89, both P〈0.01）. Conclusions DTI can quantitatively assess global and regional left ventricular systolic and diastolic function of elderly patients with DCM, and provide the reliable information for the judgment of pathogenetic condition.

关 键 词：多普勒组织成像 心肌病 扩张型 心室功能 左 

分 类 号：R542.2[医药卫生—心血管疾病]