冠脉血栓形成的中医体质特点临床研究  

Analysis of Chinese Medical Constitutions in Coronary Thrombosis Patients

作　　者：潘朝锌[1] 王庆高[1] 何新兵[1] 吴万里[1] 卢健棋[1] 李成林[1] 杨清华[1] 张振千[1] 何贵新[1] 

机构地区：[1]广西中医学院第一附属医院,广西南宁530023

出　　处：《新中医》2010年第8期16-17,共2页New Chinese Medicine

基　　金：广西卫生厅重点项目(编号:Z200934)

摘　　要：目的:观察冠脉血栓形成的中医体质特点,为早期防治冠脉血栓形成提供临床依据。方法:将冠脉造影明确为冠心病的患者根据造影结果分为2组。冠脉血栓形成组32例,无冠脉血栓形成组68例。观察2组体质分布特点、冠脉病变积分及血栓素B2(TXB2)、血管性血友病因子(vWF)。结果:冠脉血栓形成组以瘀血质、痰湿质多见,而无冠脉血栓形成组以气虚质、气郁质、阴虚质多见(P<0.01);冠脉病变积分在瘀血质、痰湿质、气虚质、气郁质、阴虚质中存在明显差异,瘀血质>痰湿质>气虚质、气郁质、阴虚质(P<0.01)。TXB2、vWF比较,瘀血质>痰湿质>气虚质、气郁质、阴虚质(P<0.05,P<0.01)。结论:冠脉血栓形成的体质以痰湿质、瘀血质多见,痰湿质、瘀血质之人易处于高凝状态,容易形成血栓。Objective: To analyze the characteristics of Chinese medical constitution in patients with coronary thrombosis,thus to supply evidence for the early prevention of coronary thrombosis. Methods: Patients with confirmed coronary heart disease were randomized into 2 groups: 32 patients with coronary thrombosis were in the positive group,and 68 without coronary thrombosis were in the negative group. The distribution of constitution types,scores of coronary pathological changes,and levels of thromboxan B2 (TXB2 ) and von Willebrand factor (vWF) were observed. Results: In the positive group,the constitution of blood stasis and phlegm dampness was dominant;in the negative group,the constitution of Qi deficiency,Qi stagnation and yin deficiency was dominant ( P < 0. 01 ).The scores of coronary pathological changes were the highest in blood-stasis constitution,higher in phlegm-dampness constitution,and high in the constitution of Qi deficiency,Qi stagnation and yin deficiency ( P < 0. 01),so did the TXB2 and vWF levels ( P < 0. 05 or P < 0. 01 ).Conclusion: The constitution of coronary thrombosis patients is dominated by phlegm dampness and blood stasis.

关 键 词：冠脉血栓 冠状动脉疾病 中医体质 体质分型 

分 类 号：R541.4[医药卫生—心血管疾病]