高龄急性冠脉综合征患者经皮冠状动脉支架治疗的临床观察  

Clinical outcome in octogenarians with acute coronary syndrome after percutaneous coronary intervention

作　　者：刘冬生[1] 赵红磊[1] 何如平[1] 苏少辉[1] 李大强[1] 

机构地区：[1]东莞市人民医院心内科,广东东莞523400

出　　处：《现代生物医学进展》2010年第13期2518-2520,共3页Progress in Modern Biomedicine

摘　　要：目的:评价高龄急性冠脉综合征(acute coronary syndrome,ACS)患者行经皮冠状动脉介入(percutaneous coronary intervention,PCI)治疗的安全性和有效性。方法:对比分析108例高龄ACS患者(≥75岁组)和176例非高龄ACS患者(<75岁组)冠状动脉造影特征、PCI治疗的情况,即刻手术成功率、住院及随访期间主要心血管事件的发生情况。结果:高龄组与非高龄组比较,冠状动脉病变多为多支病变(72.2%比31.8%,P<001);2组手术即刻成功率无明显差异;2组术后达到心肌梗塞溶栓(thrombolysis in myo-cardial infarction,TIMI)3级血流患者比率无明显差异;高龄组手术操作时间非高龄组长[(68.4±25.4)min比(53.7±21.8)min,P<0.05];高龄组住院期间、随访期间累计总的主要心血管事件发生率明显高于非高龄组。结论:对高龄ACS患者行PCI治疗是比较安全而有效的再灌注手段。Objectives：To evaluate the safety and eficacy of primary percutaneous coronary intervention（PCI）in patients with acute coronary syndrome（ACS） over 75 years old.Methods：The data of patients who were underwent PC1 during April 2005 to April 2008 were analyzed retrospectively.They were divided into the elderly acute coronary syndrome（ACS） group（≥75 years,n=108） and the younger group（〈75years,n=176）.The immediate success rate and major adverse cardiac events（MACE） in two groups were analyzed during in-hospital duration and follow-up period.Results：Compared with the younger group,the elder group were likely to have multi-vessels lesions.The time of procedure was longer in elder group than in the younger group.There was no significant on the immediate success rate and the rate of thrombolysis in myocardial infarction（TIMI）flow 3 between two groups.Compared with the younger group,the incidence of MACE were higher in elder group during in-hospital and follow-up period,too.Conclusions：PCI is also a relatively safe and effective reperfusion method in elder patients with ACS.

关 键 词：冠状动脉疾病 血管成形术 经腔 经皮冠状动脉 预后 

分 类 号：R541.4[医药卫生—心血管疾病]