机构地区:[1]中国医学科学院基础医学研究所北京协和医学院基础学院生理学与病理生理学系,北京100005 [2]流行病学与统计学系
出 处:《中华预防医学杂志》2010年第8期706-710,共5页Chinese Journal of Preventive Medicine
摘 要:目的研究成年女性身体脂肪含量及分布与肺通气功能的关系。方法采用多阶段整群抽样法抽取黑龙江省部分地区19—81岁健康成年女性935名,每10岁为一个年龄段。首先通过问卷调查了解基本情况,然后测量其身高、体重、腰围、臀围、身体成分和肺功能,分析体脂百分比(PBF)和腰臀比(WHR)与用力呼气肺活量(FVC)、用力呼气一秒量(FEVl)、一秒率、最大呼气流量(PEF)、用力呼出25%肺活量时呼气流量(FEF25%)、用力呼出50%肺活量时呼气流量(FEF50%)、用力呼出75%肺活量时呼气流量(FEF75%)和最大呼气中段流量(MMEF)等肺通气功能指标的关系。结果19—29岁组、≥60岁组女性PBF分别为(16.89±5.34)%、(24.39±6.83)%,WHR分别为0.77±0.05、0.88±0.06;PBF和WHR有随年龄增长而增大的趋势(F=50.11,P〈0.01)。19~29岁组、≥60岁组女性PBF肥胖率分别为3.23%(7/217)、43.75%(28/64),WHR肥胖率分别为19.35%(42/217)、85.94%(55/64);PBF肥胖率和WHR肥胖率随年龄增长呈上升趋势(X2值分别为161.66、159.61,P值均〈0.01)。PBF正常组和肥胖组相比,后者肺通气功能明显降低,其中FEF50%降低2.61%、FEF75%降低19.44%、MMEF降低10.28%。同样,W'ItR正常组和肥胖组相比,后者肺通气功能明显降低,其中FEF50%降低7.61%、FEF75%降低23.15%、MMEF降低12.04%。在校正年龄、身高和体质指数(BMI)因素后,PBF与FVC、FEV1、PEF、FEF25%呈负相关(,值分别为-0.14、-0.14、-0.07、-0.07,P值均〈0.05);WHR与FEV1呈负相关(r=-0.07,P〈0.05)。结论成年女性PBF升高和中心性肥胖可能是肺通气功能损伤的风险因素。Objective To examine the effect of body fat mass and fat distribution on pulmonary ventilatory function among the adult females. Methods Based on the multistage cluster sampling principal, we selected 935 healthy adult females with ages of 19 - 81 years old in Heilongjiang province to conduct the study. Every 10 - years old as a age group. Firstly obtain the basic situation through the questionnaire survey, and then measure the height, body weight, waistline, hip circumference, body composition and lung function. FVC, FEV1, PEF, FEF25%, FEF50% , FEF75% and MMEF were determined. This study also examined the relationships between percentage body fat ( PBF), waist-hip ratio ( WHR ) and FVC, FEV1, PEF,FEF25% ,FEFSO% ,FEF75% ,MMEF. Results PBF of subjects with ages of 19 -29 years old and over60 years old were (16.89 ±5.34)% and(24.39 ±6.83)%,WHR were 0.77±0.05 and 0.88 ± 0. 06, respectively. PBF and WHR tended to increase with age ( F = 50. 11, P value 〈 0. 01 ). PBF obesity rates of subjects with ages of 19 -29 years old and over 60 years old were 3.23% (7/217)and 43.75% (28/64) , WHR obesity rates were 19. 35 % ( 42/217 ) and 85.94% ( 55/64 ) respectively. PBF obesity rate and WHR obesity rate tended to increase with age ( ~5 = 161.66, P value 〈 0. 01 ; Х^2 = 159. 61, P value 〈 0. 01 ). PBF obesity groups compared with the normal groups, the former pulmonary ventilation function reduced significantly, of which FEFS0%, FEF75% and MMEF decreased 2. 61%, 19.44% , 10. 28%, respectively. WHR obesity groups compared with the normal groups,the former pulmonary ventilation function reduced significantly,of which FEFS0%, FEF75% and MMEF decreased 7.61% ,23.15%, 12. 04%. After adjustment of age, height and body mass index (BMI), PBF was negatively correlated with FVC, FEV1, PEF and FEF25% (r values were -0. 14, -0. 14, -0. 07, -0. 07,respectively,all P values 〈0. 05) ;WHR was negatively correlated with FEV1 ( r value was - 0. 07, P value 〈 0. 05 ) after adjus
分 类 号:R195[医药卫生—卫生统计学]
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