复方甘草酸苷注射液治疗新生儿高胆红素血症68例效果观察  

Observation on the effect of compound Glycyrrhizin injection in the treatment of 68 newborn infants with neonatal hyperbilirubinemia

作　　者：邱学兰[1] 孔芹[1] 史长宏[1] 孙秀英[1] 冯集蕴[1] 

机构地区：[1]滕州市中心人民医院,山东滕州277500

出　　处：《齐鲁护理杂志（下旬刊）》2010年第7期24-25,共2页Journal of Qilu Nursing

摘　　要：目的：探讨复方甘草酸苷注射液治疗新生儿高胆红素血症临床效果。方法：将136例高胆红素血症患者随机分为治疗组和对照组各68例，两组均给予常规治疗，治疗组静滴复方甘草酸苷注射液3ml／kg，1次／d，5～7d为1个疗程；对照组静滴苦黄注射液1ml／kg，1次／d，5—7d为1个疗程。治疗结束后复查肝功能及血生化。结果：治疗组1个疗程后，总胆红素、AST、GGT下降值与对照组比较差异有统计学意义（P〈0．01），治愈率、平均住院日及医疗费用与对照组比较差异有统计学意义（P〈0．01）。结论：复方甘草酸苷注射液对治疗新生儿高胆红素血症有效，较苦黄注射漓疗糟．涣治俞率高彳幸院叶闻橱陕井帝用饭．Objective ： To evaluate the clinical effect of compound Glyeyrrhizin injection in the treatment of neonatal hyper- bilirubinemia. Methods： 136 newborn infants with neonatal hyperbilirubinemia were randomly divided into treatment group and control group （68 cases for each group ）. Conventional treatment was adopted in both groups. The patients in the treatment group were intravenously given compound Glycyrrhizin injection 3 ml / kg once a day, 5 - 7 days were taken as a course of treatment and the patients in the control group were intravenously given Kuhuang injection 1 ml / kg one time per day, 5 - 7 days were taken as a course of treatment. The liver function and blood biochemical indexes were examined and tested again after treatment. Results ： There were statistically significant differences in the comparison of decreased values of total bilirubin, AST and GGT after treatment for one week between the two groups （P 〈 0.01 ） ; the comparison of cure rater the average length of hospitalization and medical costs was significantly different between the two groups （ P 〈 0.01 ）.Conclusion ： The curative effect of compound Glyeyrrhizin injection in treatment of neonatal hyperibirubinemia was affirmative and its effect is faster, cure rate is higher, length of hospitalization is shorter and medical costs is lower compared with usage of Kuhuang injection.

关 键 词：复方甘草酸苷注射液 新生儿 高胆红素血症 护理 

分 类 号：R473.72[医药卫生—护理学]