聊城市2009年手足口病重症病例流行病学特征分析  

Analysis of Epidemiological characteristics of severe cases of Hand - Foot - Mouth Disease in 2009 in Laocheng

作　　者：张世英[1] 杨金英[1] 张蕾[1] 谢春阳[1] 

机构地区：[1]聊城市疾病预防控制中心,山东聊城252100

出　　处：《中外医学研究》2010年第15期91-93,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的 分析2009年聊城市手足口病重症病例流行病学特征,了解聊城市2009年重症患儿的地区分布,探索聊城市手足口病重症患儿发病高危因素,最大限度的减少重症病例的发生,为控制手足口病提供科学依据.方法 收集整理聊城市2009年各级各类医疗机构报告的手足口病报告卡信息及2009年RT-PCR实验室检测结果,应用描述性方法 进行流行病学分析,利用Mapinfo软件制作地图.自行设计调查表,对50例重症患者开展流行病学调查.结果 2009年聊城市手足口病报告发病16 018例,发病率277.60/10万,重症641例,重症发生率4%,死亡3例,病死率为0.02%.全市8个县区均有手足口病重症病例报告.县区之间报告发病率差异有统计学意义（P〈0.01）.4～9月为报告重症发病高峰.重症病例年龄分布以小年龄组为主,5岁以下儿童报告发病634例,占总重症病例数的98.91%,1岁组患儿重症发生率最高,远高于全市的重症发生率（4.0%）,且有统计学意义（or值=2.13）.共检测65份样本,EV71阳性率为12.3%.结论 聊城市手足口病防控形势严峻,手足口病的发生有明显的年龄、性别、季节和地区差异.对来自重点地区5岁以下年龄组手足口病患者应提高警惕,及早救治,加强健康教育宣传,同时加强手足口病监测工作,提高实验室检测能力建设.Objective To analyze the epidemiological characteristic of severe cases of hand - foot - mouth disease （HFMD） in Liaocheng, learn the geographical distribution of children with severe, minimize the occurrence of severe cases,and provide scientific evidence for controlling and preventing measures. Methods Collected the data of hand - foot - mouth disease in Liaocheng in 2009 , analyzed the data by descriptive epidemiology method ,and used Mapinfo software to make maps. Some patients were diagnosed through RT - PCR. Results 16, 018 HFMD eases were reported with the incidence rate of 277.60/100,000. 641 cases of severe was reported with the severe incidence rate of 4% . 3 died and the case fatality rate was 0.02%. The severe cases of HFMD were reported in every counties and districts. There were significant differences of the HFMD incidences among the counties and districts （P 〈0. 0l ）. The peak of severe hand -foot -mouth disease was from April to September. 98.91% severe cases were less than 5 years old. 65 specimens were detected. The positive rate of EV71 was 12. 3%. Conclusion The prevalence of HFMD was serious in Liaocheng. Incidence were different among ages,sexes, seasons and places. The children aged under 5 from key areas should be vigilant and treated eralily, while strengthening the hand - foot - mouth disease surveillance and laboratory capacity - building.

关 键 词：手足口病 重症 流行病学 分析 

分 类 号：R511.1[医药卫生—内科学]