室温条件下4-OH-TEMPO体系高效选择催化氧化苄醇为醛的研究  

Moderate and selective aerobic oxidization of benzyl alcohols to corresponding aldehydes catalyzed by 4-OH-TEMPO system

作　　者：尚洁[1,2] 赵文军[1] 王华[1,2] 王旭[1,2] 杨丹红[1] 

机构地区：[1]中国科学院新疆理化技术研究所,新疆乌鲁木齐830011 [2]中国科学院研究生院,北京100049

出　　处：《应用化工》2010年第7期997-1000,共4页Applied Chemical Industry

基　　金：新疆维吾尔自治区自然科学基金项目(200821158)

摘　　要：报道了以TMEDA(N,N,N’,N’-四甲基乙二胺)为促进剂,与4-OH-TEMPO(4-羟基-2,2,4,4,-四甲基-哌啶氮氧自由基)和CuC l组成催化体系,在室温条件下用空气为氧化剂高转化率、高选择性催化氧化苄醇为相应芳香醛的方法,氧化速率快。研究结果表明,胺在4-O-TEMPO催化体系中起到重要作用,碱的促进作用与胺的碱性和空间位阻有关,TMEDAD的效果最佳。The system of 4-OH-TEMPO/CuCl/TMEDA has been developed for selectively oxidizing benzyl alcohols to the corresponding aldehydes using air as the terminal oxidant at room temperature.The reaction was accomplished in a short time and the isolated yield was high.The results showed that amine played an important role in the catalytic system.The tertiary aliphatic amine with small stereo-hindrance and strong alkalinity has strong promotion in the catalytic system.TMEDA has the best promoting effect.

关 键 词：4-OH-TEMPO TMEDA 氯化亚铜 苄醇 选择氧化 

分 类 号：O625.34[理学—有机化学]