肾移植受体93例生存质量调查研究  

Quality of life in 93 renal transplantation recipients

作　　者：周山[1] 刘宏[1] 余荣杰[1] 赵洪雯[1] 李敛[1] 吴雄飞[1] 

机构地区：[1]第三军医大学西南医院肾内科,重庆400038

出　　处：《第三军医大学学报》2010年第15期1652-1655,共4页Journal of Third Military Medical University

基　　金：西南医院临床创新基金(SWH2006A003)~~

摘　　要：目的回顾性调查研究肾移植受者的生存质量状况及相关影响因素。方法采用国际通用SF-36、症状经历量表、焦虑抑郁量表以及自制一般资料量表对1998-2008年在我院行肾移植手术并且移植肾良好的93例肾移植受者进行回顾性调查。结果肾移植受者生存质量显著优于血液透析患者(P<0.01);男性、家庭成员年总收入较高、文化程度较高、术后返回工作的肾移植受者生存质量较好;肾移植受者在术后的存活过程中普遍经历多种症状(13.37±7.41)种,症状经历的多少与生存质量之间存在统计学差异(P<0.05);肾移植受者的焦虑、抑郁状况显著优于透析患者(P<0.01)。多因素回归分析显示,症状经历是生存质量躯体健康方面和心理健康最显著影响因素(标准偏回归系数0.477和0.649),焦虑、抑郁状况是生存质量心理健康方面重要影响因素(标准偏回归系数0.281)。结论肾移植术后患者生存质量较血液透析患者改善,但仍受到多种因素影响,需要采用标准量表测量并有针对性地进行关注。症状经历与焦虑抑郁状况是影响肾移植受者生存质量最显著的因素。Objective To retrospectively investigate the quality of life （QOL） of renal transplantation recipients and its related influence factors. Methods QOL of 93 renal transplantation recipients who received operation from 1998 to 2008 was respectively investigated with SF-36, ESRD-SCL, HAD and self-made general information scales. Another 68 patients with chronic renal dysfuction who had recieved hemodialysis for （ 19.86 ± 13. 57） months served as control. Results The QOL of renal transplantation recipients was much better than that of hemodialysis patients （P 〈 0.01 ）. Males, members with a higher income or a higher education level, and those who returned to work had a better QOL. Various symptoms occurred in patients after renal transplantation （13.37±7.41）. The number of symptoms in patients was closely related with their QOL （P 〈0.05）. The anxiety and depression levels were lower in renal transplantation recipients than in hemodialysis patients （P 〈0.01 ）. Multi-factor regression analysis demonstrated that symptom was the most efficient factor that influenced the physical health and mental health of QOL （ standard partial regression coefficient 0.477 and 0. 649 respectively）. Anxiety and depression were the most important factors on mental health of QOL （standard partial regression coefficient 0. 281 ）. Conclusion The QOL of renal transplantation recipients is better than that of hemodialysis patients. However, it can be influenced by many factors, which should there be investigated with standard scales and closely concerned. Symptoms, anxiety and depression are the most important factors influencing the QOL of renal transplantation recipients.

关 键 词：肾移植受者 生存质量 SF-36 ESRD-SCL 

分 类 号：R195.4[医药卫生—卫生统计学] R617[医药卫生—卫生事业管理]