二羟丙茶碱预防老年全麻手术后肺部感染  

Application of Diprophyline to Prevent Aged Patients from Postoperational Pulmonary Infection

作　　者：马静[1] 邢宝平[1] 唐素娟[1] 

机构地区：[1]安徽省蚌埠市第一人民医院普外科,233000

出　　处：《中华全科医学》2010年第9期1116-1117,共2页Chinese Journal of General Practice

摘　　要：目的探讨支气管扩张药物二羟丙茶碱(喘定)对老年上腹部手术患者行呼吸道全麻后预防肺部感染的作用。方法将65岁以上(含65岁)在全麻下行上腹部手术的老年患者随机分为实验组与对照组,实验组于术后当天至第4天每天给予喘定0.75mg,对照组其他治疗与实验组相同,但不给予喘定。术后1周内观察两组患者肺部感染情况。结果实验组29例,其中COPD2例,发生肺部感染2例;对照组31例,COPD3例,发生肺部感染7例。实验组无COPD的病例与对照组相比,肺部感染发生差异有统计学意义(P<0.05),有COPD的病例之间差异无统计学意义(P>0.05)。结论老年上腹部手术行呼吸道全麻的患者术后应用二羟丙茶碱,可抑制支气管痉挛,有效促进排痰,减少肺泡内炎性渗出,明显减少肺部感染发生率。Objective To investigate effect of diprophyline on preventing aged patient from pulmonary infection after their upabdominal operation with general anesthesia.Methods 60 aged upabdominal operation cases were randomly divided into 2 groups,trial and control,29 cases in trial and others in control.The both received the same treatment except the former was postoperatively given 0.75 mg diprophyline for 4 days from the opday while their pulmonary symptoms were being observed to see whether they had postoperative pulmonary infection.Results There were 2 cases of COPD and 2 cases of postoperative pulmonary infection in trial and 3 cases of COPD and 7 cases of pulmonary infection in control.According to T test,in the two groups,SPSS 11.0 Caculation showed difference in pulmonary infection（P〈0.05）,but no difference in COPD（P〉0.05）.Conclusion For aged patients after their upabdominal operation with general anesthesia,diprophyline is an good inhibitor for their bronchospasm.So it can effectively improve their spitting,decrease vesicular effusion and relieve the pulmonary infection.

关 键 词：老年 呼吸道全麻 手术后 二羟丙茶碱 肺部感染 

分 类 号：R614[医药卫生—麻醉学]