2005～2009年张家港市28家医院分娩的围产儿出生缺陷监测分析  

Analysis on Surveillance of Birth Defects among Perinatal Infants in 28 Hospitals of Zhangjiagang City,2005-2009

作　　者：查建梅 傅军[2] 

机构地区：[1]张家港市妇幼保健所,江苏张家港215600 [2]张家港市疾病预防控制中心,江苏张家港215600

出　　处：《预防医学论坛》2010年第8期751-754,共4页Preventive Medicine Tribune

摘　　要：[目的]了解张家港市2005～2009年出生缺陷发生情况,为进一步减少出生缺陷,制定预防保健措施及开展干预工作提供依据。[方法]对2005～2009年在张家港市28家医院分娩的围产儿出生缺陷监测资料进行描述性分析。[结果]2005～2009年累计检测围产儿47740名,监测时间延长至产后3个月的出生缺陷儿739例,出生缺陷发生率为154.79/万,孕28周至产后7天出生缺陷发生率为46.50/万(P<0.01)。739例出生缺陷中,先天性心脏病501例,总唇腭裂64例,多指多趾24例,小耳23例,神经管畸形16例,其他112例。出生缺陷发生率(/万),2005～2009年分别为104.93、147.21、173.04、179.39、157.17(P<0.01);农村为163.85,城区为128.13(P<0.01);男婴为164.79,女婴为142.38(P<0.05);母亲年龄<20岁、20～34岁、>34岁的分别为551.72、149.79、217.32(P<0.01);母亲文化程度小学及以下、初中、高中、大专及以上的分别为135.57、177.29、163.65、122.55(P<0.01)。[结论]张家港市2005～2009年出生缺陷发生率较高,先天性心脏病是最为常见的出生缺陷。[Objective]To understand the occurrence of birth defects in Zhangjiagang city from 2005 to 2009 and provide evidence for prevention and health intervention measures to decrease birth defects.[Methods]Descriptive analysis was made on perinatal birth defects in 28 hospitals of Zhangjiagang city from 2005 to 2009.[Results]739 cases of birth defect were found among 47 740 cases of perinatal infants after the monitoring time extended to 3 months postpartum,the total birth defect incidence was 154.79/10^4;the birth defect incidence was 46.50/104 when monitoring time was from 28 weeks pregnant to 7 days postpartum（P〈0.01）.Among the 739 cases of birth defects,the top five diseases were congenital heart disease（501 cases）,cheilopalatognathus（64 cases）,polydactylism（24 cases）,microtia（23 cases）and neuraltube defects（16 cases）.The incidence of birth defects（/10^4）from 2005 to 2009 was 104.93,147.21,173.04,179.39,157.17P〈0.01）,in rural was 163.85 while in urban was 128.13（P〈0.01）,in male was 164.79 while in female was 142.38（P〈0.01）.For different age of mothers（20,20-34,34）,the incidence of birth defects was 551.72,149.79,217.32/10^4（P〈0.01）.For different educational background of mothers（primary school and below,junior middle school,senior middle school,junior college and above）,the birth defect was 135.57,177.29,163.65,122.55（P〈0.01）.[Conclusion]The incidence of birth defects is high in Zhangjiagang city from 2005 to 2009,and congenital heart disease is the most common birth defect.

关 键 词：围产儿 出生缺陷 监测 

分 类 号：R722[医药卫生—儿科]