脉搏传导时间技术对儿童睡眠呼吸障碍疾病诊断的意义  

Diagnostic role of pulse tansit time in children with sleep disordered breathing

作　　者：钟建文[1] 刘大波[1] 黄振云[1] 谭宗瑜[1] 邵剑波[1] 仇书要[1] 俞洁[1] 

机构地区：[1]广州市妇女儿童医疗中心广州市儿童医院耳鼻咽喉科,510120

出　　处：《中华耳鼻咽喉头颈外科杂志》2010年第8期660-663,共4页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

摘　　要：目的 探讨脉搏传导时间（pulse transit time,PTT）技术对儿童睡眠呼吸障碍疾病（sleep disordered breathing,SDB）的诊断价值.方法 通过对随机抽取的48例2～13岁因睡眠打鼾临床初步诊断为SDB患儿进行PTT和多道睡眠图（PSG）同步监测,由不同的技师和医生对两种方法的数据进行分析.结果 PSG与PTT监测得到的呼吸暂停低通气指数（AHI）、阻塞性呼吸暂停指数（OAI）、最低血氧饱和度（LSaO2）和微觉醒指数中位数[25分位数;75分位数]分别为：4.9[1.3;10.1]次/h和4.6[1.5;11.8]次/h,1.2[0.7;4.9]次/h和1.3[0.6;5.0]次/h,0.93[0.85;0.95]和0.93[0.84;0.95],14.5[12.6;16.4]次/h和26.0[17.4;30.6]次/h,AHI、OAI和LSaO2差异均无统计学意义（P值均＞0.05）,而微觉醒指数则PTT检出率高于PSG（Z=-5.19,P＜0.01）.两种设备对阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的诊断以及病情程度的判断差异均无统计学意义（P值均＞0.05）,而PTT可在不符合OSAHS诊断的患儿中识别出上气道阻力综合征.结论 PTT操作简单,可获得SDB疾病的诊断参数,临床上可用于儿童SDB疾病的诊断和分度.PTT可获得呼吸努力相关性微觉醒参数,对诊断上气道阻力综合征有意义.Objective To explore the diagnostic value of pulse transit time（PTT） in children with sleep disordered breathing（SDB）.Methods Forty eight randomly selected snorers（2-13 years）with SDB were examined by PSG and PTT in the same time. Data obtained were analyzed by different technicians respectively. Statistics and analysis of the data were performed. Results Apnea hypopnea index （AHI）,obstructive apnea index（OAI）, the lowest oxygen and micro-arousal index were obtained by PSG and PTT.The results was described as M [25 percentile; 75 percentile]：4.9[1.3; 10.1], 4.6 [1.5; 11.8]; 1.2[0.7;4.9], 1.3[0.6;5.0]; 0.93[0.85;0.95], 0.93[0.84;0.95]; 14.5[12.6;16.4], 26.0[17.4;30.6]. The difference of AHI, OAI, and the lowest oxygen were not significant （P＞0.05）, while the PTT arousal index detection rate was higher than PSG（Z=-5.19, P＜0.01）. There was no significant difference in the diagnosis of obstructive sleep apnea-hypopnea syndrome （OSAHS） and determination of degree of patient＇s condition （P＞0.05）. PTT could identify upper airway resistance syndrome in children without OASHS. Conclusions Both methods can be used to diagnose SDB. However, PTT is easy to useand suitable for the diagnosis of SDB in children, especially for UARS.

关 键 词：脉搏 多道睡眠描记术 睡眠呼吸暂停综合征 儿童 

分 类 号：R766[医药卫生—耳鼻咽喉科]