县级医院急性心肌梗死溶栓治疗现状分析  

Analysis of the status of thrombolytic therapy with acute myocardial infarction in county hospital.

作　　者：周维东[1] 

机构地区：[1]睢宁县人民医院心内科,江苏睢宁221200

出　　处：《中外医学研究》2009年第13期18-20,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的分析县级医院急性ST段抬高心肌梗死溶栓治疗现状。方法回顾性分析2006年1月～2009年6月雎宁县人民医院收治的STEMI患者的临床资料并根据是否溶栓分为溶栓组和未溶栓组。分析年龄、性别、起病－入院间期、起病－溶栓间期、吸烟、高血压病、高血脂、糖尿病、脑卒中史、心绞痛史、典型胸痛、夜间发病、入院时心功能等因素对溶栓治疗的影响。结果患者平均起病－入院间期为（427±52）min，溶栓组患者平均起病－入院间期为（298±32）min，起病－溶栓间期为（366±43）min。与溶栓组比较，未溶栓组患者年龄偏大（P〈0．05），女性患者较多（P〈0．01），合并糖尿病（P〈0．01）、心绞痛史（P〈0．05）、脑卒中史（P〈0．01）、在夜间发病（P〈0．05）的比率较高，而典型胸痛的发生率较低（P〈0．01）。结论STEMI患者的平均起病－入院间期、起病－溶栓间期明显延长，年龄偏大、女性、糖尿病、有心绞痛史、脑卒中史、夜间发病、典型胸痛是影响患者及时入院并接受溶栓治疗的相关因素。Objective To investigate the status of thrombolytic therapy of patients with acute ST - segment elevation myocardial infarction. Methods The clinical data of hospitalized patients with STEMI between January 2006 and June 2009 in Suining hospital were analyzed retrospectively and the patients were divided into two groups based on the thrombolytie therapy. Factors including age, gender, onset - admission interval, onset - thrombolysis interval, smoking, hypertension, hyperlipidemis, diabetes mellitus, previous stroke, history of angina, typical chest pain, onset at night, heart function on admission were analyzed. Results The mean onset - admission interval was（427 ± 52）min in all patients, in the group with thrombolysis, the mean onset - admission interval was （ 298± 32 ） rain, onset - thrombolysis interval was （ 366 ± 43 ） min. Compared with the patients treated with thrombolysis, the patients treated with non - thrombolysis were older（ P 〈 0.05 ）, had a higher ratio for female （ P 〈 0.01 ）, those with diabetes （ P 〈 0.01 ）, history of angina （ P 〈 0.05 ）, previous stroke （ P 〈 0.01 ）, onset at night （ P 〈 0.05 ）, as well as a less ratio for those with typical chest pain（ P 〈 0.01 ）. Conclusions Onset - admission interval and onset - thrombelysis interval for STEMI are still prolonged. Age ,female and the other items as mentioped above are the factors that influence the prompt admission and thrombolytie therapy for patients with STEMI.

关 键 词：心肌梗死 溶栓治疗 因素 

分 类 号：R542.22[医药卫生—心血管疾病]