急性心梗行急诊冠脉支架植入术联合应用氯比格雷和巴米尔的临床观察  

Clinical observation of Aacute myocardial infarction underwent emergency coronary stent implantation combined with and clopidogrel and combined with clinical observation Bamir

作　　者：高振香[1] 李晔[2] 

机构地区：[1]包头医学院第二附属医院,内蒙古014030 [2]内蒙古医学院第三附属医院

出　　处：《当代医学》2010年第17期266-267,共2页Contemporary Medicine

摘　　要：目的观察急性心梗冠状动脉成形术及支架植入(PCI)术前及术后服用抗血小板药物氯吡格雷和巴米尔对凝血功能和术后1年再狭窄发生的影响。方法行经皮腔内冠状动脉成形术及支架植入术(PCI)治疗的急性心梗患者143例,术前均服用氯比格雷300mg与巴米尔300mg,术后连续服用氯吡格雷75mg/d和巴米尔100mg/d共12个月。观察患者服药期间出血(轻微出血、严重出血)及再狭窄的发生率。结果 1例患者因自行停用药物发生再梗猝死,2例出现消化道出血,1例出现牙龈出血,142例患者经复查冠状动脉造影未发现支架内再狭窄。结论急性心梗PCI术前及术后服用氯吡格雷及巴米尔可有效预防支架内再狭窄的发生。Objective：To observe acute myocardial infarction underwent emergency coronary stent implantation combined with clopidogrel and BamirAcute myocardial infarction coronary angioplasty and stent implantation（PCI） before and after taking anti-platelet drug clopidogrel and Bamir on blood coagulation and restenosis 1 year after the impact.Methods：percutaneous Percutaneous transluminal coronary angioplasty and stent implantation（PCI） treatment of acute myocardial infarction in 143 patients,preoperatively and Bamir taking clopidogrel 300mg 300mg,postoperative clopidogrel doses,75mg /d and Bamir 100mg /d for 12 months.Bleeding（minor bleeding,major bleeding） and the incidence of restenosis were Oobserved during medication in patients with bleeding（minor bleeding,major bleeding） and the incidence of restenosis.Results：Sudden death occurred in 1 one patient because of stopped stopping taking the drug because ofits own re-infarction sudden death occurred,2 patients had gastrointestinal bleeding,1 case with gums bleeding,142 patients underwent angiographic restenosis was not found.Conclusion：Acute myocardial infarction Bamir and clopidogrel before and after PCI and Bamir taking clopidogrel is effective in preventing in-stent restenosis.

关 键 词：急性心梗 氯吡格雷 巴米尔 冠状动脉成形术及支架植入术 再狭窄 

分 类 号：R541.4[医药卫生—心血管疾病]