白内障患者围术期抗菌药物预防性应用调查与合理性评价  

Investigation of Perioperative Prophylactic Utilization of Antibiotics in Cataract Patients and Its Rationality Evaluation

作　　者：李萍[1] 刘月芬[1] 王琳[1] 隋忠国[1] 

机构地区：[1]青岛大学医学院附属医院,青岛市266003

出　　处：《中国药房》2010年第30期2815-2817,共3页China Pharmacy

摘　　要：目的:调查我院眼科白内障患者围术期抗菌药物预防性应用情况。方法:随机抽取我院眼科2009年白内障手术患者100例,对围术期应用抗菌药物种类、用药时间、给药时机、切口愈合情况、住院药品费用等进行统计、分析并进行合理性评价。结果:所有患者均在围术期全身和局部预防性应用抗菌药物(100%);全身用药包括应用乳酸左氧氟沙星(67例,占67%)、注射用头孢呋辛钠(25例,占25%)、克林霉素磷酸酯注射液(2例,占2%)、注射用头孢他啶(6例,占6%);仅术前30min给药1次63例(63%),术前30min给药1次、术后给药<24h12例(12%),二者合计75%;术前给药1次、术后给药>24h25例(25%),其中最长为4d,平均用药时间为2.5d。结论:我院不合理用药主要表现在术后应用抗菌药物时间偏长、预防用药选择不当等方面。应加强抗菌药物干预并强化医师围术期预防应用抗菌药物的合理化意识。OBJECTIVE：To investigate the perioperative prophylactic utilization of antibiotics in cataract patients in ophthalmology department of our hospital.METHODS：100 cases of cataract surgery in 2009 were randomly collected from our hospital.Category of antibiotics,administration time point,medication time,wound healing and drug costs in hospitalization period were analyzed statistically and the rationality of above indexes was evaluated.RESULTS：100 cases all received prophylactic antimicrobials by local and systematic administration in the perioperative period（100%）.Drugs for systematic administration contained Levofloxacin（n=67,67%）,Cefuroxime sodium for injection（n=25,25%）,Clindamycin phosphate injection（n=2,2%） and Ceftazidime for injection（n=6,6%）.63 cases were only given drugs 30 min before operation（63%）;12 cases were given medicine 30 min before operation and within 24 h after operation（12%）;above situation accounted for 75%.25 cases were given medicine before operation and within 24 h after operation（25%）,in which the average medication duration was 2.5 days and the longest was 4 days.CONCLUSION：The irrational use of drugs in our hospital manifests inappropriate selection and too long use of antibiotics after operation.The interference of perioperative prophylactic utilization of antibiotics should be reinforced and it is urgent to intensify consciousness of physicians about rational use of antibiotics in perioperative period.

关 键 词：白内障手术 围术期 预防用药 抗菌药物 

分 类 号：R969.3[医药卫生—药理学] R287[医药卫生—药学]