Highly efficient procedure for the conjugate addition of amines to electron deficient alkenes catalyzed by novel ionic liquid  

作　　者：QUAN NanNan BAO ShaoHua YANG JianGuo 

机构地区：[1]Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062, China

出　　处：《Chinese Science Bulletin》2010年第23期2512-2516,共5页

基　　金：supported by the National Key Project of Scientific and Technical Supporting Programs funded by Ministry of Science & Technol-ogy of China (2006BAE03B06);Shanghai Leading Academic Discipline Project (B409);Shanghai International Cooperation of Science and Technology Project (06SR07101)

摘　　要：A highly efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes.The novel ionic liquid [HO3S-bPy][FeCl4] with both Lewis and Brφnsted acid sites has been synthesized successfully for the reactions.The results show that the catalyst was very efficient for the conjugate addition of amines to electron deficient alkenes with excellent yields in several minutes.This method has several key features including operational simplicity,no need of any solvent,low cost of the catalyst used,high yields,reusability,excellent chemoselectivity,and wide applicability.A highly efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes. The novel ionic liquid [HO3S-bPy][FeCl4] with both Lewis and BrФnsted acid sites has been synthesized successfully for the reactions. The results show that the catalyst was very efficient for the conjugate addition of amines to electron deficient alkenes with excellent yields in several minutes. This method has several key features including operational simplicity, no need of any solvent, low cost of the catalyst used, high yields, reusability, excellent chemoselectivity, and wide applicability.

关 键 词：共轭烯烃 离子液体 共轭加成 催化剂 电子 程序 胺 化学选择性 

分 类 号：O622.1[理学—有机化学] O646.1[理学—化学]