阻塞性睡眠呼吸暂停低通气综合征与胰岛素抵抗关系的研究进展  

Advances in researching relationship between obstructive sleep apnea-hypopnea syndrome and insulin resistance

作　　者：韩书芝[1] 李冲[1] 平芬[1] 

机构地区：[1]河北省人民医院老年病三科,石家庄050051

出　　处：《国际呼吸杂志》2010年第15期933-935,共3页International Journal of Respiration

摘　　要：有研究表明,中心性肥胖是阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的主要危险因素,可导致胰岛素抵抗.OSAHS患者存在胰岛素抵抗,中心性肥胖可能是联系OSAHS和胰岛素抵抗的中间环节.早期开展经鼻持续气道正压通气治疗OSAHS,可提高组织对胰岛素的敏感性,促进组织对葡萄糖摄取利用,从而减轻或避免产生胰岛素抵抗.The studys have provided evidence that abdominal obesity is important factor in obstructive sleep aphea-hypopnea syndrome may lead to insulin resistance. Severe insulin resistance exists in obstructive sleep apnea-hypopnea syndrome. Abdominal obesity may be the central factor in the relationship between obstructive sleep apnea-hypopnea syndrome and insulin resistance. Treatment with continuous positive airway pressure may improve the sensitvity of insulin, increase the usage of glucose, decrease the insulin resistance.

关 键 词：阻塞性睡眠呼吸暂停低通气综合征 中心性肥胖 胰岛素抵抗 

分 类 号：R766[医药卫生—耳鼻咽喉科]