2009年呼吸内科下呼吸道感染患者病原菌分布及耐药性分析  

Pathogen distribution and drug resistance in patients with lower respiratory tract infection in 2009

作　　者：田利奇[1] 黄少丹[1] 曹梅[1] 邝锦辉[1] 

机构地区：[1]广州医学院第二附属医院呼吸内科,510260

出　　处：《中国现代药物应用》2010年第15期8-9,共2页Chinese Journal of Modern Drug Application

摘　　要：目的了解2009年呼吸内科下呼吸道感染患者的病原菌种类分布及其耐药性。方法对呼吸内科病房下呼吸道感染住院患者痰菌培养阳性标本进行回顾性分析。结果革兰阴性杆菌占76.5%,依次为铜绿假单胞菌、不动杆菌属、大肠埃希菌、肺炎克雷伯菌,对亚胺培南、头孢哌酮/舒巴坦、阿米卡星耐药率为0.0%～40%;革兰阳性球菌占17.4%,仅对万古霉素耐药率为0;真菌占6.1%。结论呼吸内科下呼吸道感染病原菌,主要为革兰阴性杆菌,病原菌耐药现象严重,加强耐药性监测,合理应用抗菌药物十分重要。Objective To investigate the distribution and resistance of pathogenic bacteria isolated from patients with lower respiratory tract infection in Department of Respiratory Medicine in 2009. Methods We analyzed the pathgens isolated from the sputum of patients with lower respiratory tract infection by the retrospective methods. Results Gram-negative bacteria were 75. 6% . The most important Gram-negative pathgens were Pseudomonas aeruginosa、Enterobacter cloacae、Escherichia coli and Klebsiella Pneumoniae,respectively, the drug resistance ratio to imipenem,cefoperzone/salbactam and amikacin was 0. 0% ～ 40% ; Gram-positive bacteria were 17. 4% ,only for vancomycin the drug resistance ratio is 0. 0% ; Fungi were 6. 1% . Conclusion Gram-negative bacilli are the major pathgens in lower respiratory tract infection in Department of Respiratory Medicine,the drug resistance is severe,it is important to utilize antibiotics reasonably and pay attention to supervising drug resistance.

关 键 词：下呼吸道感染 病原菌 耐药性 

分 类 号：R446.5[医药卫生—诊断学]