产程潜伏期应用哌替啶或地西泮对产程和新生儿的影响  

The effects of pethidine or diazepam used in latent period on stage of labor and neonate

作　　者：张建平[1] 邝健全[1] 范侠[1] 李青[1] 

机构地区：[1]中山医科大学孙逸仙纪念医院妇产科

出　　处：《新医学》1999年第5期263-264,共2页Journal of New Medicine

摘　　要：目的：探讨产程中应用哌替啶或地西泮对产程和新生儿呼吸的影响。方法：采用随机对照方法，对１５０例处于潜伏期的产妇分别用哌替啶（Ａ组５０例）、地西泮（Ｂ组５０例）和安慰剂（Ｃ组５０例），观察产程进展情况、新生儿脐血ｐＨ值、氧分压（ＰＯ２）和二氧化碳分压（ＰＣＯ２）。结果：应用哌替啶或地西泮对第一产程有明显促进作用（Ｐ＜０．０５），但对第二产程无明显影响（Ｐ＞０．０５），两药对产程的影响差异无显著性（Ｐ＞０．０５），对脐血ｐＨ值、氧分压和二氧化碳分压均无明显影响（Ｐ＞０．０５）。结论：潜伏期应用哌替啶或地西泮可促进第一产程进展，且对胎儿无明显呼吸抑制作用。Objective: To investigate the effects of pethidine or diazepam on stage of labor and neonatal breath Method: 150 primiparae in latent period were divided randomly into three groups: group A ( n =50) given with pethidine, group B ( n =50) given with diazepam and group C ( n =50) given with Vitamin B 1 Both the first and se cond stage courses were observed, and the pH, PO 2 and PCO 2 of umbilical cord arterial or venous blood were measured Results: Pethidine and diazepam accelerated course of the first stage ( P <0 05), but unaffected and the course of the second stage in three the values of pH, PO 2 and PCO 2 of umbilical cord arterial and venous blood in the three groups ( P >0 05) Conclusion: Pethidine or diazepam used in latent period can shorten the course of the first stage, but can not inhibit neonatal breath

关 键 词：哌替啶 地西泮 新生儿 血气分析 产程 潜伏期 

分 类 号：R714.45[医药卫生—妇产科学]