高血压勺型与非勺型动态变异性与颈动脉内膜-中层厚度的关系分析  

The Relationship Analysis of Ambulatory Blood Pressure Variation with Intima Thickness of Carotid Artery in Dipper and Non-dipper Essential Hypertension Patients

作　　者：刘利宏[1] 唐成玥 

机构地区：[1]双流县第一人民医院,四川成都610200

出　　处：《现代临床医学》2010年第4期265-266,共2页Journal of Modern Clinical Medicine

摘　　要：目的:探讨原发性高血压勺型与非勺型者动态血压变异性(blood pressure Variability,BPV)与颈动脉内膜-中层厚度(IMT)的关系。方法:回顾性分析163例高血压病患者24 h动态血压监测(ABPM)及其同期颈动脉内膜-中层厚度,以各时间段每30 min血压均值的标准差(s)作为血压变异性的指标。结果:①非勺型高血压组患者血压变异性各项参数值与勺型组比较均有明显增高。②24 h收缩压变异性(24hSS)和白昼收缩压变异性(dSS)、夜间收缩压变异性(nSS)及夜间舒张压变异性(nDS)IMT>1.0 mm组大于IMT≤1.0 mm组。③24hSS、nSS、nDS与颈动脉内膜-中层增厚均呈显著正相关。结论:非勺型高血压病患者血压变异性更大,且颈动脉内膜-中层厚度增厚者血压变异性更大。Objective：To study the correlation of ambulatory blood pressure variation and intima thickness of carotid artery in patients with essential hypertension by comparing parameters between the dipper and non-dipper hypertension.Methods：The 24 hours ambulatory blood pressure monitoring（ABPM） and the simultaneous intima thickness of carotid artery in 163 cases of the dipper and non-dipper hypertensive patients were retrospectively analysed.We used the standard deviation（SD） of blood pressure mean in every 30 minutes periods as the index of blood pressure variance.Results：Compared dipper group with non-dipper group,presented obvious increase in each parameter values of ambulatory blood pressure variation.The IMT1.0mm group exceed IMT≤1.0mm group in 24 hours contractive pressure variance and daytime contractive pressure variance,nighttime contractive pressure variance and diastolic pressure variance.The 24 hours contractive pressure variance、nighttime contractive pressure variance and diastolic pressure variance were all significant positive correlation with intima thickness of carotid artery.Conclusion：Comparing with dipper cases non-dipper cases have larger blood pressure variance;and the more blood pressure variance are in thickening IMT cases.

关 键 词：动态血压变异性 颈动脉内膜-中层厚度 勺型与非勺型血压 

分 类 号：R544.1[医药卫生—心血管疾病]