鼻息肉患者中Samter三联征的调查,1例报告和30年中文文献回顾  

Clinical investigation for Samter triad,a case report and review of 30 years chinese associated literature

作　　者：李小敏[1] 樊韵平[2] 冯韶燕[2] 夏文彤[2] 

机构地区：[1]广东省珠海市人民医院耳鼻咽喉科,珠海519000 [2]中山大学附属第五医院耳鼻咽喉科,珠海519020

出　　处：《中华哮喘杂志（电子版）》2010年第3期156-160,共5页Chinese Journal of Asthma(Electronic Version)

摘　　要：目的调查鼻息肉患者中伴发支气管哮喘(简称哮喘)和Samter三联征的情况并复习相关中文文献。方法前瞻性351例慢性鼻鼻窦炎和鼻息肉患者中的哮喘和Samter三联征的发生率;计算机检索中国知识资料总库中阿司匹林哮喘和Samter三联征的相关报道。结果通过47个月内调查351例住院手术的慢性鼻鼻窦炎患者,结果只发现了1例Samter三联征的病例。通过对30年内中文文献进行检索,共收集到45篇关于阿司匹林哮喘或是Samter三联征的报道,其中含有病例数分别是346例和141例。其中来自北方的报道病例远多于南方。结论相对中国庞大的哮喘和鼻息肉患者群,Samter三联征是一种少见病;通过与国外报道对比,我们推测:中国人中Samter三联征的发生率较低。Objective Investigate the prevalence of bronchial asthma （asthma） and Samter triad in the patients of chronic rhinosinusitis,and review the associated literature published in Chinese. Methods Investigate prospectively the comorbidity of asthma and Samter triad in patients of chronic rhinosinusitis, whereafter search and review associated literature published in Chinese out of the China Academic Journal Network Publishing Database. Results We found only one Samter triad case for 351 consecutive patients during 47 months. From the 30 years Chinese associated literature, we searched out 45 papers which consisted of 341 aspirin-induced asthma and 141 Samter triad cases;and the papers and cases from north china is far more than that from south china. Conclusions Given the gigantic population of asthma out of Chinese,Samter triad is still a rare disease. Compared with the reported prevalence in western population, we presume that the prevalence of Samter triad in Chinese is at lower level.

关 键 词：鼻息肉 鼻鼻窦炎 阿司匹林不耐受 哮喘 Samter三联征 阿司匹林哮喘 

分 类 号：R187-55[医药卫生—流行病学]