关于硒缺乏与儿童反复呼吸道感染关系的初步研究  

The relationship between selenium deficiency and repeated respiratory infection in children

作　　者：张爱启[1] 孙丽艳[2] 付姝丽[1] 

机构地区：[1]哈尔滨医科大学附属第二医院,哈尔滨150086 [2]哈尔滨医科大学地方病控制中心大骨节病研究所

出　　处：《中国地方病防治》2010年第4期272-273,共2页Chinese Journal of Control of Endemic Diseases

摘　　要：目的检测反复呼吸道感染患儿血硒水平及进行补硒治疗,探讨硒缺乏与儿童发生RR I之间的关系,为临床治疗提供依据。方法病例组选取4岁龄RR I患儿60例,随机分为常规治疗组与补硒组。常规治疗组与补硒组均给予抗感染及对症治疗,补硒组另进行补硒治疗。病例组随访6个月,复查血清硒水平,观察并记录呼吸道感染的复发次数,进行t检验。对照组健康4岁儿童30例,检测其血清硒水平与病例组进行比较,进行方差分析。结果病例组血清硒水平低于对照组,两组比较其差异有统计学意义(P<0.05);采用不同的方法治疗后两病例组的呼吸道感染复发次数比较有显著差异(P<0.05)。结论RR I患儿血清中硒水平低于正常健康儿童;硒缺乏与儿童RR I有关。Objective To measure the levels of selenium and to reinforce selenium in children with repeated respiratory infection（RRI） in order to discuss the relationship between selenium deficiency and RRI in children.Methods Sixty children with RRI were randomly divided into two groups,two groups were performed routine treatment but the selenium group add the selenium.The case group was followed up six months and measured the levels of selenium once more besides to observe the frequence of recurrence.T-test was done.Thirty age and sexy matched healthy controls were enrolled in this study.The levels of selenium were measured and ANOVA was done.Results The mean concentration of selenium in RRI group was lower than that of the control group（P〈0.05）.The frequence of recurrence in group with routine treatment was higher than the other group（P〈0.05）.Conclusion Selenium levels in children with RRI are lower than those in normal children;Selenium are connected with the happening of RRI in children.

关 键 词：硒缺乏 反复呼吸道感染 血清硒水平 儿童 

分 类 号：O613.52[理学—无机化学]