磷酸二氢钠催化芳樟醇合成香叶基丙酮的研究  

Synthesis of geranylacetone from linalool catalyzed by sodium dihydrophosphate

作　　者：杨海宽[1] 吴志平[1] 李湘洲[1] 杨国恩[1] 孟维[1] 

机构地区：[1]中南林业科技大学材料科学与工程学院,湖南长沙410006

出　　处：《日用化学工业》2010年第4期266-269,共4页China Surfactant Detergent & Cosmetics

摘　　要：采用NaH2PO4.2H2O作催化剂催化芳樟醇合成香叶基丙酮。研究了反应温度、物料摩尔比、催化剂用量和反应时间对产率的影响,通过单因素实验和正交试验得到较佳工艺条件为:反应温度170℃,n(芳樟醇)∶n(乙酰乙酸乙酯)=1∶2.2,w(催化剂)=3%,反应8 h,得到产物产率达97.5%。正交试验结果表明各因素对合成反应影响顺序为:反应温度>反应时间>物料摩尔比>催化剂用量。Geranylacetone was prepared with linalool and ethyl acetoacetate as starting materials,and NaH2PO4·2H2O as catalyst.The optimum process conditions were defined by studying the effect of the reaction temperature,molar ratio,dosage of the catalyst and reaction time on the yield of the synthesis reaction.The optimized conditions identified via single factor tests and orthogonal experimental test are：reaction temperature of 170 ℃,n（linalool）∶n（ethyl acetoacetate）=1∶2.2,w（NaH2PO4·2H2O）=3% and reaction time of 8 h,the best yield achieves 97.5%.The sequence of the factors that affect the reaction yield was identified as：reaction temperature〉reaction time〉molar ratio〉dosage of the catalyst.

关 键 词：香叶基丙酮 磷酸二氢钠 芳樟醇 催化 

分 类 号：TQ655[化学工程—精细化工]