血必净注射液治疗重型颅脑损伤的临床研究  

Clinical Effects of Xuebijing Injection in Severe Craniocerebral Injury

作　　者：张元峰[1] 张保朝[1] 王中礼[1] 刘建生[1] 张建党[1] 

机构地区：[1]河南省南阳市中心医院神经外科,河南南阳473009

出　　处：《医学综述》2010年第16期2526-2528,共3页Medical Recapitulate

摘　　要：目的分析血必净注射液对重型颅脑损伤患者的格拉斯哥昏迷评分、C反应蛋白以及头颅CT的影响。方法将72例患者随机分为对照组和试验组,对照组采用单纯西医综合治疗,试验组在应用原有西药的基础上加用血必净注射液,7d为1个疗程,连用2个疗程。记录患者的格拉斯哥昏迷评分,测定血清中C反应蛋白水平,观察患者的脑水肿程度。结果急性期内对照组和试验组的病死率分别为22.22%、2.78%,差异有统计学意义(P<0.05)。入院后,同期试验组和对照组格拉斯哥昏迷评分、C反应蛋白水平、脑水肿程度间差异均有统计学意义(P<0.05)。结论在西医综合治疗的基础上加用血必净注射液利于重型颅脑损伤患者格拉斯哥昏迷评分的提高,更快地降低血清C反应蛋白水平,减轻脑水肿。Objective To analyze the effects of Xuebijing injection in patients with severe craniocerebral injury（SCI） on GCS score,CRP and head CT.Methods A total of 72 patients were enrolled,using a simple machine-based grouping.The control group was treated with TCM and Western medicine alone while the experimental group was supplemented with Xuebijing injection,for two courses of 7 days.GCS,serum CRP and cerebral edema were appropriately measured.Results The mortality in acute phase was 22.22% and 2.78% in control group and treatment group in a statistically significant manner（P〈0.05）.Additionally,GCS,CRP and brain edema in treatment group differed significantly from control group（P〈0.05）.Conclusion On the basis of treatment with Western medicine,the of use Xuebijing injection might be more beneficial for the improvement of GCS score in patients with SCI,quickly reduce serum CRP and brain edema.

关 键 词：重型颅脑损伤 血必净注射液 格拉斯哥昏迷评分 C反应蛋白 

分 类 号：R651.15[医药卫生—外科学]