澂江县人群伤寒副伤寒抗体水平及病原学检测  

Etiological and antibodies′detection for typhoid and paratyphoid bacillus among different population in Chengjiang

作　　者：王建全 李虹 伏晓庆[2] 李鸿坤 马重义 

机构地区：[1]云南省澂江县疾病预防控制中心,云南澂江652500 [2]云南省疾病预防控制中心,昆明650022

出　　处：《中国卫生检验杂志》2010年第7期1733-1734,共2页Chinese Journal of Health Laboratory Technology

基　　金：卫生公益性行业科研专项经费(200802025)

摘　　要：目的:了解澂江县不同人群抗体水平及病原学情况,为伤寒副伤寒的预防和控制提供依据。方法:收集疫情资料,对不同人群伤寒副伤寒抗体水平及病原学进行监测,对分离到的菌株进行耐药分析。结果:正常人群抗体水平测定O抗体≥80为17.51%,H抗体≥80为4.3%;重点人群监测血培养阳性率2.97%,均为甲型副伤寒沙门菌;抗体监测阳性率33.13%;药敏试验对阿莫西林/棒酸100%敏感,利福平100%耐药。结论:我县流行的为甲型副伤寒,对同一份血标本用抗体水平及病原学两种方法同时检测以提高检出的阳性率;人群隐形感染较为普遍,应采取综合性的防控措施进行预防和控制。Objective：To aquire the antibody titer for typhoid and paratyphoid and the bacterial epidemic situation among different population in Chengjiang and then to help prevent and control typhoid and paratyphoid.Methods：Basal datas were collected from different population and then the typhoid and paratyphoid bacterials and their antibodies were detected.The separated bacterials were used for drug resistance analysis.Results：Antibody type O≥80 were 17.51% and antibody type H ≥80 were 4.3% among ordinary population.The blood cuture results showed that the bacterial prevalence rates were 2.97% and the antibody serum positive rates were 33.13% among special population（with temperature≥37.5℃ at least for three days） and all the detected bacterials were paretyphoid type A.Drug sensitive test showed 100% of the bacterials were sensitive to Amoxicillin/clavulanate potassium and resistant to Rifampicin.Conclusion：Paratyphoid type A was epidemic in Chengjiang.The use of both etiology and antibody tests for one serum specimen would enhance positive rate.Subclinical infection were common among ordinary people.Comprehensive measures should be taken to prevent and control the typhoid and paratyphoid in Chengjiang.

关 键 词：伤寒副伤寒 抗体水平 病原学 耐药率 

分 类 号：R516.3[医药卫生—内科学]