围产期因素对极低出生体重儿暂时性低甲状腺素血症的影响  

The impact of perinatal factors on transient hypothyroxinemia in very-low-birth-weight infants

作　　者：贝斐 郭薇薇 黄萍[1] 孙建华[1] 

机构地区：[1]上海交通大学医学院附属上海儿童医学中心新生儿科,200127

出　　处：《中华内分泌代谢杂志》2010年第7期583-585,共3页Chinese Journal of Endocrinology and Metabolism

摘　　要：调查早产极低出生体重儿生后早期甲状腺激素水平的动态变化及其发生暂时性低甲状腺素血症的围产期危险因素.7日龄时TT4值为（61.03±24.19）nmol/L,暂时性低甲状腺素血症的发生率为12.05%（n=10）;肺表面活性物质应用（OR=14.25,95%CI 2.61～70.07）、机械通气（OR：13.76,95%CI2.55～68.05）、多巴胺应用（OR=9.45,95%CI2.26～39.5）以及胎龄≤30周（OR=5.78,95%CI1.36～24.49）是早产极低出生体重儿发生暂时性低甲状腺素血症的危险因素.The perinatal risk factors of transient hypothyroxinemia（TH） in premature very-low-birth-weight infants （VLBWI） was investigated by longitudinally assessing thyroid hormones concentrations during their early life after birth and analyzing the relationship to perinatal factors. The serum TT4 concentration on day 7 was （61.03±24.19）nmol/L and the incidence of TH was 12. 05% （n= 10）. Pulmonary surfactant support （ OR = 14.25, 95% CI2. 61-70. 07）, ventilation support （ OR = 13. 76,95% CI 2. 55-68. 05） , dopamine support （ OR = 9.45, 95% CI 2. 26-39. 5 ） , and gestational age less than 30 weeks （ OR = 5. 78,95% CI 1. 36-24. 49） were perinatal risk factors for TH of premature VLBWI.

关 键 词：甲状腺激素 早产 极低出生体重儿 甲状腺功能减退 

分 类 号：R722.6[医药卫生—儿科]