104例抗菌药物不良反应/事件报告分析  

Analysis of 104 Cases of Adverse Drug Reaction Reports of Antibacterial Agents

作　　者：李国誉[1] 林红宁[1] 

机构地区：[1]肇庆市第一人民医院药剂科,广东肇庆526021

出　　处：《中国药物警戒》2010年第8期498-500,共3页Chinese Journal of Pharmacovigilance

摘　　要：目的了解和分析抗菌药物发生不良反应/事件的大致情况,为临床合理使用抗菌药物提供依据和参考。方法对我市某医院2009年104例抗菌药物所致不良反应/事件报告进行分析。结果 104例不良反应/事件报告中,女性略多于男性;18～59岁年龄段的成年患者占多数;以静脉滴注给药为主(72例,占69.23%);以头孢菌素类发生不良反应的例数最多(40例,占38.46%);不良反应的类型以皮肤及其附件损害最常见(54例,占51.92%)。结论医疗机构应重视抗菌药物的不良反应,加强抗菌药物临床应用的监管。Objective To investigate the situation of adverse drug reaction/event（ADR/ADE） of antibacterial agents,thus to provide bases and references for rational use of antibacterial agents.Methods 104 ADR reports of antibacterial agentswere collected and analyzed in a hospital during 2009.Result Of the total 104 ADR reports,females was slightly more than males;adult patients between 18 to 59 years old age were accounted for the majority;72 cases that administered intravenously were accounted for the majority（69.23%）;the cases that caused by cephalosporins were accounted for the most（40 cases,38.46%）,and damage to the skin and accessories（54 cases,51.92%）was the commonest type.Conclusion We should pay great attention to the ADR of antibacterial agents,and strengthen the supervision of clinical application of antibacterial agents.

关 键 词：抗菌药物 药品不良反应/事件 

分 类 号：R916.693[医药卫生—药学] R994.11