靶点射频热凝联合臭氧注射治疗腰椎间盘突出症的临床观察  

TREATMENT OF LUMBAR DISC HERNIATION BY TARGET RADIOFREQUENCY THERMOCOAGULATION COMBINED WITH OZONE INJECTION

作　　者：伍建平[1] 赵序利[1] 谢珺田[1] 宋文阁[1] 傅志俭[1] 

机构地区：[1]山东大学附属省立医院疼痛科,济南250021

出　　处：《中国疼痛医学杂志》2010年第4期204-207,共4页Chinese Journal of Pain Medicine

基　　金：山东省自然科学基金(Y2006C69);国家自然科学基金项目(30972844)资助课题

摘　　要：目的:观察C臂引导下靶点射频热凝联合臭氧注射治疗腰椎间盘突出症的临床效果及安全性。方法:将100例腰椎间盘突出症患者分为两组,A组在C型臂X光机定位下行靶点射频热凝联合臭氧注射治疗(n=50),B组在C型臂X光机定位下行胶原酶溶盘治疗(n=50)。比较两组患者的住院时间、治疗前、治疗后第4天VAS变化、并发症发生率、治疗后1个月、6个月、12个月的疗效。结果:A组住院时间明显短于B组,两组治疗前及治疗后第四天VAS、治疗1、6、12个月的疗效、总并发症发生率相比均无显著统计学差异。结论:靶点射频热凝联合臭氧注射腰椎间盘突出症的临床疗效及安全性与胶原蛋白酶溶盘治疗相似,但接受靶点射频热凝联合臭氧注射治疗的患者住院时间更短。Objective： To investigate the efficacy and safety of target radiofrequency thermocoagulation combined with ozone injection to the lumbar disc herniation under the guidance of C-armed X-ray fluoroscopy. Methods： 100 patients were divided into two groups. Group A received target radiofrequency thermocoagulation combined with ozone injection under the guidance of C-armed X-ray fluoroscopy（ n =50）. Group B were injected with collagenase under the guidance of C-armed X-ray fluoroscopy （ n = 50）. The average time of hospitalization, the change of VAS before and after the treatment of the first four days, postoperative complication rate, the effects after one month, six months and twelve months were recorded. Results： The average time of hospitalization of group A was significantly shorter than that of group B. There were no significant differences of the change of VAS of admission and after the treatment of the first four days, postoperative complication rate, the effects after one month, six months and twelve months. Conclusion： The effect and safety of target radiofrequency thermocoagulation combined with ozone injection for the treatment of LDH is equal to the injection of collagenase. The average of hospitalization of target radiofrequency thermocoagulation combined with ozone injection was significantly shorter than that of the injection of collagenase.

关 键 词：臭氧 腰椎间盘突出症 靶点射频热凝 胶原蛋白酶 

分 类 号：R681.53[医药卫生—骨科学]