心脏外科重症监护病房病原菌分布与耐药分析  

Distribution and Drug Resistance of Pathogenic Bacteria in Intensive Care Unit of Cardiac Surgery

作　　者：于洪泉[1] 王振国[1] 臧红星[1] 王春芳[1] 杨学勇[1] 刘旭[1] 王韬渊[1] 陈燕[2] 张明华[3] 

机构地区：[1]武警医学院附属医院心脏外科,天津300162 [2]武警医学院附属医院感染控制科,天津300162 [3]武警医学院附属医院检验科,天津300162

出　　处：《中华医院感染学杂志》2010年第15期2340-2341,共2页Chinese Journal of Nosocomiology

摘　　要：目的分析心脏外科重症监护病房(ICU)病原菌感染的临床分布及耐药特点,确定更有效的抗菌药物使用对策。方法回顾性分析该院心脏外科ICU 2006年6月-2007年12月送检标本自实验室获得的所有病原菌学检查阳性的结果和相关的药敏试验结果。结果在207份阳性标本结果中,痰液的主要常见病原菌依次为:铜绿假单胞菌、白色假丝酵母菌、金黄色葡萄球菌、肺炎克雷伯菌、大肠埃希菌分别为22.2%、18.3%、16.3%、15.4%、7.7%;血液标本中常见前5种病原菌依次为:铜绿假单胞菌、肺炎克雷伯菌、产气肠杆菌、弗氏柠檬酸杆菌、金黄色葡萄球菌分别为23.0%、15.4%、15.4%、15.4%、7.7%。结论心脏外科ICU发生感染的主要病原菌是铜绿假单胞菌,其血液与痰培养阳性标本的药物敏感性及耐药性存在不同。OBJECTIVE To analyze the antibiotic resistance and the bacteria distribution in the cardiac surgery intensive care unit for choosing more suitable antibiotic.METHODS A retrospectively analysis of all of the positive results of bacteria culture and drug resistance from the simples taken from the intensive care unit of cardiac surgery during the period from Jun 2006 to Dec 2007 was conducted.RESULTS The frequency ordering of pathogenic bacteria in the sputum was as follows Pseudomonas aeruginosa 22.1%,Candida albicans 18.3%,Staphylococcus aureus 16.3%,Klebsiella pneumoniae 15.4%,and Escherichia coli 7.7%,while the ordering in the blood was P.aeruginosa 23.0%,K.pneumoniae 15.4%,Enterobacter aerogenes 15.4%,Citrobacter freundii 15.4%,and S.aureus 7.7%.CONCLUSIONS The Gram-negative organisms are the main pathogenic bacteria in our intensive care unit of cardiac surgery.The bacteria cultured from blood have the deferent antibiotic resistance in comparison with that from sputum.

关 键 词：铜绿假单胞菌 耐药性分析 抗菌药物 重症监护病房 心脏外科 

分 类 号：R378[医药卫生—病原生物学]