2-(1-苯基-3-芳基吡唑-4-基)-3-芳酰氨基-4-噻唑啉酮的合成  

Syntheses of 2-(1-Phenyl-3-aryl-1H-pyrazol-4-yl)-3-arylamido-4-thiazolidinones

作　　者：周玉强[1] 马玉洁[1] 曹玲华[1] 

机构地区：[1]新疆大学化学化工学院,乌鲁木齐830046

出　　处：《化学通报》2010年第8期746-749,共4页Chemistry

基　　金：国家自然科学基金项目(20462006);新疆植物资源与天然产物化学重点实验室项目资助

摘　　要：1-苯基-3-芳基-4-甲酰基吡唑与芳酰肼在乙醇中回流,缩合所得的腙在巯基乙酸作用下,合环得到2-(1-苯基-3-芳基吡唑-4-基)-3-芳酰氨基-4-噻唑啉酮类化合物,其结构经IR,MS,1HNMR谱和元素分析确证。A series of 2-（1-phenyl-3-arylpyrazol-4-yl）-3-arylamido-4-thiazolidinones were synthesized via two steps reaction,that is,the reaction of 1-phenyl-3-aryl-4-formylpyrazole with aroylhydrazines in ethanol and closed ring under the action of mercaptoacetic acid.The structures of as-synthesized compounds were characterized by IR,MS,1 H NMR and elemental analysis.

关 键 词：4-甲酰基吡唑 芳酰肼 噻唑啉酮 

分 类 号：TQ252.1[化学工程—有机化工]