基于模型的磁共振乳腺温度成像方法  

Model-based magnetic resonance temperature mapping method for the human breast

作　　者：潘昕怿[1] 李诚[1] 应葵[1] 秦文[2] 李坤成[2] 

机构地区：[1]清华大学工程物理系,粒子技术与辐射成像教育部重点实验室,北京100084 [2]首都医科大学附属宣武医院放射科,北京100053

出　　处：《清华大学学报（自然科学版）》2010年第8期1149-1153,共5页Journal of Tsinghua University(Science and Technology)

基　　金：中外医学磁共振学术交流基金资助项目(N4-011)

摘　　要：为解决传统相位法和波谱法在乳腺热疗温度监控应用中的局限,提出一种基于内在参照物模型的磁共振乳腺温度成像方法。通过扩展原有温度模型并结合频率辨识算法,使该方法能够在多成分乳腺频谱中筛选出水和脂肪频率,进而计算温度。4名志愿者参加了实验。常温下初步测温结果表明:该方法能减少运动等因素干扰,测温误差比仅使用水质子频率时显著降低,空间分辨率达到2mm×2mm×5mm,而温度空间分布不均匀性在±10℃左右。An internal-reference model-based magnetic resonance （MR） thermometry method was developed to overcome the limitations of conventional phase mapping and spectroscopic methods for temperature monitoring during breast thermal therapy. A modified model and the frequency identification algorithm identify the water and fat frequencies from the multi-species breast spectrum for the temperature calculation. Experimental results at room temperature from four volunteers demonstrate that the method reduces the effects of tissue motion with the errors being less than those using only the water frequency, while the spatial resolution is improved to 2 mm×2 mm×5 mm. The spatial temperature variation is about ±10 ℃.

关 键 词：磁共振温度成像 基于模型 乳腺 水质子共振频率 频率辨识 

分 类 号：R445.2[医药卫生—影像医学与核医学]