胶束电动力学毛细管色谱中有机调节剂对溶质容量因子的影响  

The Effect of Organic Modifier on the Capacity Factor of the Solute in the Micellar Electrokinetic Capillary Chromatography

作　　者：张维冰[1] 张云[1] 许国旺[1] 张玉奎[1] 

机构地区：[1]中国科学院大连化学物理研究所色谱开放实验室

出　　处：《色谱》1999年第2期119-122,共4页Chinese Journal of Chromatography

基　　金：国家自然科学基金!29775024

摘　　要：将质量作用定律应用于胶束电动力学毛细管色谱中溶质、有机添加剂和胶束之间的相互作用研究，得到了溶质容是因子与各过程平衡常数及有机添加剂、表面活性剂浓度的关系的数学表达式。进一步分析表明，研究调节剂在胶束中可能有一定的溶解度，但这一过程对于胶束在电泳过程中的迁移速度几乎没有影响；有机添加剂对溶质容量因子的影响主要反映为其对表面活性剂临界胶束浓度的影响，在一级调节剂浓度不变的情况下，溶质容基因子与表面活性剂浓度之间满足很好的线性关系。In this paper the mass action law has been used to study the relationship of solute, organic modifier and micelle in the micellar electrokinetic capillary chromatography. A series of equations were given showing the relationship of capacity factor (k) of the solute, equivalent constant, concentration of solute and migration speed under the condition of using only one organic modifier. The results showed that the organic modifier can, to some extent, be dissolved in micelles. It has almost no effect on micellar actual migration speed, but, the organic modifier influences the CMC of surfactants and the distribution of solutes between two phases and results in the change of the capacity factors of the solutes. No simple equations like those in HPLC can be used to show the effect of organic modifier and surfactants on k. At the first approximation,they have the following equation, 1nk ≈ a + bCB + clnCBwhere, CB is the total concentration of organic modifier, a, b and c are constants.

关 键 词：毛细管色谱 有机调节剂 容量因子 溶质 MEKC 

分 类 号：O657.803[理学—分析化学]