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作 者:史春志[1] 殷兆芳[1] 严毓勤[1] 吴士尧[1] 冯义柏[1]
机构地区:[1]上海交通大学医学院附属第九人民医院心脏科,上海市200011
出 处:《心血管康复医学杂志》2010年第4期436-438,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine
摘 要:目的:探讨组织多普勒(TDI)综合射血等容期指数[Tei,(二尖瓣关闭~开放时间-主动脉射血时间/主动脉射血时间)]评价尿毒症心肌损害程度的价值. 方法:85例尿毒症患者根据二维超声心动图(2D)心肌回声强度等指标分为心肌损害逐渐加重之Ⅰ、Ⅱ、Ⅲ组(n=30,32,23),分别进行2D各项参数及左室射血分数(LVEF)、短轴缩短率(FS)、心搏指数(SI)测定,并利用脉冲多普勒(PWD)测定二尖瓣血流频谱E峰、A峰、E/A比值,同时利用TDI技术检测二尖瓣瓣环运动频谱,获取TDI-Tei,并与30例正常人(正常对照组)进行比较,分析不同组间各项指标差异. 结果:与正常对照组比较,尿毒症Ⅱ、Ⅲ组的LVEF[(65.30±7.42)%∶(54.01±10.63)%、(47.35±10.67)%], FS [(32.86±6.31)%∶ (26.78±6.03)%、(23.29±6.08)%] 显著下降(P〈0.01), SI [(41.75±8.61)ml/m^2∶(50.73±10.86)ml/m^2、(52.09±9.53)ml/m^2]显著升高(P〈0.01),Ⅰ组与正常对照组比较则无显著性差异.与正常对照组比较, 尿毒症3组TDI-Tei均显著升高,且Ⅰ、Ⅱ、Ⅲ组的水平依次显著升高[(0.36±0.13)、 (0.57±0.29)、(0.74±0.36)、(0.87±0.26)] P〈0.01. 结论:TDI-Tei是较传统超声心动图指标更为敏感的,评价尿毒症心功能损害程度无创指标.Objective: To evaluate the value of evaluation of Tel index by tissue-Doppler imaging (TDI) on heart function in patients with uremia. Methods: A total of 85 uremia patients were divided into Ⅰ , Ⅱ, Ⅲ groups (n=30, 32, 23 respectively) by the myocardial texture characterization, and 30 normal persons were regard as normal control group. The routine indexes of 2D echocardiography were measured. Meanwhile Tei index (Tei) was measured by TDI (TDI- Tel) in each group. Results: Compared with normal control group, the left ventricular ejection fraction (LVEF) [ (65.30±7.42)% vs. (54.01±10.63)%0, (47.35±10.67)% ], fractional shortening (FS) [ (32.86± 6.31) % vs. (26.78±6.03) %, (23. 29±6.08) %] significantly decreased (P〈0.01 all), stroke index (SI) [ (41.75 ± 8.61) ml/m^2 vs. (50. 73±10.86) ml/m^2, (52.09±9.53) ml/m^2] significantly increased (P〈0.01) in Ⅱ, Ⅲ groups of uremia patients, but compared with normal control group these parameters of Ⅰ group were not significant different. Compared with normal control group, the TDI-Tei of Ⅰ , Ⅱ, Ⅲ groups of uremia patients significantly increased [ (0.36±0. 13) , (0.57±0.29), (0.74±0.36), (0.87±0.26)] , and among Ⅰ , Ⅱ, Ⅲ groups all significantly increased (P〈0.01 all). Conclusion: Tel index is a more sensitive parameter to evaluate the degree of heart function lesion in uremia patients.
分 类 号:R542.2[医药卫生—心血管疾病]
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