老年重症肺部感染患者血清降钙素原水平测定的临床意义  

The detection of serum procalcitonin level in the elderly with severe pneumonia and the clinical significance

作　　者：常婷婷[1] 王翎[1] 潘旭东[1] 李洁[1] 毛燕青[1] 祝丽晶[1] 

机构地区：[1]苏州大学附属第一医院特需病区,江苏苏州215006

出　　处：《中国老年学杂志》2010年第15期2091-2093,共3页Chinese Journal of Gerontology

基　　金：国家自然科学基金资助项目(30330540);江苏省卫生厅重点学科基金资助(No.200319)

摘　　要：目的探讨血清降钙素原在老年重症肺部感染患者中的临床意义。方法收集47例重症肺部感染患者(重症组)、30例非重症肺部感染患者(非重症组)、30例除外感染性疾病的患者(非感染组)、30例体检健康者(健康组),分别测定各组血清降钙素原、超敏C反应蛋白、白细胞计数及体温,并进行比较分析。结果重症组的血清降钙素原浓度与非重症组、非感染组及健康组比较差异均有统计学意义(P<0.05);而重症组的超敏C反应蛋白、白细胞计数及体温与非重症组比较差异均无统计学意义(P>0.05)。结论血清降钙素原与老年肺部感染的严重程度密切相关,血清降钙素原可作为预测和识别老年人重症肺部感染的辅助诊断指标。Objective To investigate the value of serum procalcitonin （PCT） determination for risk evaluation in aged patients with severe pneumonia.Methods The levels of serum PCT,high sensitive C-reactive protein （hs-CRP）,white blood cell count and temperature were measured in 47 patients with severe pneumonia （severe group）,30 cases of mild to moderate pneumonia （non-severe group）,30 cases except the infection diseases （non-infection group） and 30 normal healthy persons （healthy group）.The differences of the levels of them among the groups were compared.Results There was obvious difference between severe group and the other three groups in the level of serum PCT （P0.05）,but there was no difference between severe group and non-severe group in the levels of hs-CRP and WBC （P0.05）.Conclusions Serum PCT may play an important role in aged patients with severe pneumonia.The level of serum PCT can be regarded as an auxiliary diagnosis index for aged patients with severe pneumonia.

关 键 词：老年人 重症肺部感染 血清降钙素原 

分 类 号：R563.1[医药卫生—呼吸系统]