感染性心内膜炎82例临床特点及病原菌的回顾性分析  

Retrospective analysis of clinical features and pathogens of 82 infective endocarditis patients

作　　者：陈坷[1,2,3] 褚俊[1,2,3] 陈莉[1,4] 徐健[1,2,3] 张小玲[1,2,3] 严激[1,2,3] 

机构地区：[1]安徽医科大学附属省立医院 [2]安徽省立医院心内科 [3]安徽省心血管病研究所,合肥230001 [4]安徽省立医院干一科,合肥230001

出　　处：《中国临床保健杂志》2010年第4期349-351,共3页Chinese Journal of Clinical Healthcare

摘　　要：目的探讨感染性心内膜炎的临床特点并对病原菌作出分析。方法收集感染性心内膜炎82例,并对其临床特点和38例血培养阳性菌株进行回顾性分析。结果感染性心内膜炎基础疾病谱发生改变,心脏超声检出赘生物的阳性率明显高于血培养的阳性率(75.6%vs46.3%),耐甲氧西林凝固酶阴性葡萄球菌导致的感染性心内膜炎增加,利奈唑胺对葡萄球菌导致的感染性心内膜炎疗效确切。结论感染性心内膜炎基础病因及病原菌发生变化,在选择抗菌药物时要重视针对耐甲氧西林凝固酶阴性葡萄球菌的治疗。Objective To investigate the clinical features and pathogens of infective endocarditis patients. Methods A total of 82 patients with infective endocarditis during 2000-2009 were collected. 38 cases had positive blood culture,then bacterial identification and antibiotic susceptibility tese were done. Results The fundamental diseases of infective endocarditis had changed. The positive rate of neoplasms checked by ultrasonic cardiography was higher than that of blood culture. Methicillin resistant coagulase-negative staphylococci increased recently. Linezolid had been proven to be effective for the treatment of patients with infective endocarditis. Conclusion The fundamental heart diseases of infective endocarditis and pathogens had changed. It is important to think much of methicillin resistant coagulase-negative staphylococci when we choose the antimicrobial therapies.

关 键 词：心内膜炎 症状和体征 甲氧西林抗药性 

分 类 号：R542.41[医药卫生—心血管疾病]