冠心病患者血清葡萄糖和果糖胺测定的临床应用  

The correlation between serum fructosamine and high blood glucose in patients with coronary heart disease

作　　者：陈莉[1,2] 郑芳[3] 

机构地区：[1]武汉大学,在职研究生430000 [2]咸宁市中心医院 [3]武汉大学中南医院检验科,430000

出　　处：《中国现代医药杂志》2010年第8期47-48,共2页Modern Medicine Journal of China

摘　　要：目的探讨冠心病患者高血糖和果糖胺之间的关系。方法测定35例冠心病合并糖尿病患者和38例无糖尿病的冠心病患者的血清葡萄糖和果糖胺浓度。结果冠心病合并糖尿病组及无糖尿病的冠心病组的血糖水平分别为(9.58±1.30)mmol/L、(5.16±0.60)mmol/L,都明显高于正常对照组(4.78±0.55)mmol/L,P<0.05。冠心病合并糖尿病组果糖胺(280±62)μmol/L,显著高于正常对照组果糖胺(180±35)μmol/L,P<0.05,糖尿病组与无糖尿病组患者的果糖胺水平比较有显著差异(P<0.05),但无糖尿病冠心病组果糖胺水平(180±68)μmol/L与正常对照组比较却无显著差异(P>0.05)。结论联合检测血糖与果糖胺对冠心病患者血糖增高的原因有鉴别价值。Objective To explore the correlation between serum fructosamine（FMN）and high blood glucose in patients with coronary heart disease.Methods Serum fructosamine（FMN）and blood glucose were detected in 35 patients with coronary artery disease complicated with diabetes mellitus and 38 patients with coronary artery disease imcomplicated with diabetes mellitus.Results The level of blood glucose in patients with coronary heart disease complicated with diabetes mellitus and patients with coronary heart disease imcomplicated with diabetes mellitus（9.58±1.30）mmol/L,（5.16±0.60）mmol/L was significantly higher than the normol control group（4.78 ±0.55mol/L）,P 0.05.The level of serum fructosamine was significantly higher in patients with coronary heart disease complicated with diabetes mellitus（280±62）μmol/L than the normol control group（180±35）μmol/L,P0.05.There was great differences in the level of serum fructosamine between patients with coronary heart disease complicated with diabetes mellitus and patients only with coronary heart disease（P0.05）.But there was no differences in the level of serum fructosamine between patients only with coronary heart disease（180±68）μmol/L and the normol control group（P0.05）.Conclusion The detection of fructosamine and blood glucose may contribute to analyse the cause of the high gluose in patients with coronary heart disease.

关 键 词：冠心病 糖尿病 血糖 果糖胺 

分 类 号：R541.4[医药卫生—心血管疾病]