新型辅料在中药分散片中的应用  

Application of New Accessories in Traditional Chinese Medicine Dispersible Tablets

作　　者：王艳荣[1,2] 李慧[1] 张保献[1] 王跃生[1] 张凌[2] 

机构地区：[1]中国中医科学院中药研究所,北京100700 [2]江西中医学院,南昌330004

出　　处：《中国实验方剂学杂志》2010年第10期207-209,213,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家"十一五"支撑计划(2006BAI09B08-06);重大新药创制(2009ZX0930-005-05)

摘　　要：目的:综述近几年来在中药分散片中常用的新型辅料的性质及辅料对中药分散片质量的影响,为新型辅料的开发和研究提供参考。方法:查阅国内外文献资料并进行分析和综述。结果:分散片处方中的崩解剂、黏合剂及其他新型辅料均能影响分散片崩解和溶出性能。结论:辅料的性质、配比或用量对中药分散片的质量都有较大影响。Objective：This paper reviews the characteristics of the new adjuvant commonly used in the dispersible tablets of traditional Chinese medicine and its impacts on the quality,hence to provide reference for the development and study of new adjuvant. Method：Accessing to domestic and foreign literature,we analyze and give a brief review about the new adjuvant. Result：In the tablet formulation,disintegrants,adhesives and other new adjuvant can affect the dispersible and dissolution performance of the dispersible tablets. Conclusion：The nature,ratio and amount of adjuvant all have a great impact on the quality of dispersible tablets of the Chinese medicine.

关 键 词：新型辅料 处方 中药分散片 质量 

分 类 号：R283.6[医药卫生—中药学]