405例冠心病患者冠状动脉造影结果与中医证型的相关性  

Correlation between Coronary Angiography Results and TCM Syndromes in 405 Patients with Coronary Heart Disease

作　　者：任毅[1] 陈可冀[2] 张敏州[1] 尤士杰[3] 张健[3] 盛小刚[1] 欧爱华[1] 

机构地区：[1]广东省中医院重症监护室 [2]中国中医科学院西苑医院 [3]中国医学科学院阜外心血管病医院

出　　处：《中医杂志》2010年第8期725-728,共4页Journal of Traditional Chinese Medicine

基　　金：广东省科技计划资助项目(2002C30805)

摘　　要：目的探讨冠心病患者冠状动脉造影结果与中医证型之间的关系,寻求辨证防治冠心病的客观化指标。方法对405例冠心病患者进行冠状动脉造影检查和中医辨证分型,分析不同证型、证型相兼虚实与冠状动脉病变支数、Gensini积分的关系。结果 405例冠心病患者中医证型分布由多到少排列为血瘀证>痰浊证>气虚证>阴虚证>气滞证>寒凝证>阳虚证。冠状动脉单支病变126例(31.1%),双支病变135例(33.3%),三支病变144例(35.6%)。血瘀证和痰浊证以三支病变为主,气滞证以单支病变为主(P<0.05);气虚证、阳虚证、气滞证及血瘀证的Gensini计分组间比较有统计学差异(P<0.05);单一证型的单支病变最多,复合证型的双支、三支病变较多(P<0.05);实证中单支病变最多,虚证以双支病变最多,本虚标实证则以三支病变最多(P<0.05);Gensini分数随着兼夹证的增多而增大(P<0.05)。结论冠心病中医不同证型间冠状动脉病变情况存在差异,随着证型兼夹增多冠状动脉病变程度加重,冠状动脉造影结果与冠心病中医证型存在一定相关性。Objective To explore the correlation between coronary angiography （CAG） results and TCM syndromes in the patients with coronary heart disease （CHD） to search for the objective indices for prevention and treatment based on syndrome differentiation. Methods Totally 405 CHD patients were given CAG examination and diagnosed by TCM syndrome differentiation. An analysis was carried out to study the correlations among the different TCM syndromes, complicated syndromes, number of diseased coronary artery branches, and Gensini scores. Results The TCM syndrome distribution in 405 CHD patients from more to less was blood stasis syn- drome ~ phlegm-turbid syndrome 〉 Qi deficiency syndrome 〉 Yin deficiency syndrome 〉 Qi stagnation syndrome 〉 cold coagulation syndrome 〉 Yang deficiency syndrome. There were 126 cases with one diseased artery branch （31.1 %）, 135 cases with two diseased artery branches （33. 3%）, 144 cases with three diseased artery branches （35. 6%）. The blood stasis syndrome and phlegm-turbid syndrome were mainly in those cases with three diseased artery branches, and Qi stagnation syndrome was common in those with one diseased artery branch （P〈0.05）. Gensini scores of Qi deficiency syndrome, Yang deficiency syndrome, Qi stagnation syndrome, and blood stasis syndrome were significantly different （P〈0.05）. The cases with one diseased artery branch were mostly seen in the simple syndromes, whilst those with two or three diseased artery branches mostly were seen in complicated syndromes （P〈 0. 05）. In the excess syndromes, most cases were with one diseased artery branch. In the deficiency syndromes, most cases were with two diseased artery branches. And in the complicated Ben-deficiency with Biao-excess syndromes, most cases were with three diseased artery branches （P〈0.05）. The Gensini score became increased with the increase of number of complicated syndromes （P〈0.05）. Conclusion There is difference in the severity of diseased coronary arteries and TCM

关 键 词：冠心病 冠状动脉造影 中医证型相关性 

分 类 号：R259[医药卫生—中西医结合]